274-59-9

Basic information

• Product Name: 1,2,3-TRIAZOLO(1,5-A)PYRIDINE
• Synonyms: 1,2,3-TRIAZOLO(1,5-A)PYRIDINE;triazolo[1,5-a]pyridine
• CAS NO: 274-59-9
• Molecular Formula: C₆H₅N₃
• Molecular Weight: 119.12
• Mol File: 274-59-9.mol
• Article Data: 18

Chemical Properties

• Melting Point: 39-40 C
• Boiling Point: 106-109 °C(Press: 0.6 Torr)
• Appearance: /
• Density: 1.29 g/cm³
• Refractive Index: 1.689
• PKA: 1.17±0.30(Predicted)
• CAS DataBase Reference: 1,2,3-TRIAZOLO(1,5-A)PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3-TRIAZOLO(1,5-A)PYRIDINE(274-59-9)
• EPA Substance Registry System: 1,2,3-TRIAZOLO(1,5-A)PYRIDINE(274-59-9)

Safety Data

• Hazard Codes: Xi,C
• Statements: 34
• Safety Statements: 26-27-36/37/39-45
• Hazardous Substances Data: 274-59-9(Hazardous Substances Data)

Usage

General Description

1,2,3-Triazolo(1,5-a)pyridine is a chemical compound that belongs to the class of organic compounds known as heteroaromatic compounds. These are compounds containing an aromatic ring where a carbon atom is replaced by a heteroatom. 1,2,3-Triazolo(1,5-a)pyridine is characterized by a triazole group (a five-membered ring consisting of two carbon atoms and three nitrogen atoms) connected to a pyridine group (a six-membered ring with five carbon atoms and one nitrogen atom). 1,2,3-TRIAZOLO(1,5-A)PYRIDINE has potential importance in various fields such as medicinal chemistry due to its heterocyclic nature.

InChI:InChI=1/C6H5N3/c1-2-4-9-6(3-1)5-7-8-9/h1-5H

Upstream product

• 22353-29-3 4-methyl-N'-(pyridin-2-ylmethylene)benzenesulfonohydrazide 
• 1658-42-0 methyl 2-pyridylacetate 
• 87838-56-0 triazolo<1,5-a>pyridine-3-carboxylic acid 
• 109-06-8 α-picoline 
• 3731-51-9 2-(Aminomethyl)pyridine 
• 1121-60-4 pyridine-2-carbaldehyde 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 25976-65-2 2-pyridinecarboxaldehyde hydrazone 
• 82315-59-1 4-nitrophenyl([1,2,3]triazolo[1,5-a]pyridin-7-yl)methanol 
• 78539-98-7 (E)-pyridin-2-ylmethylene-hydrazine 

Downstream Products

• 96461-37-9 3,5-dinitro-benzoic acid-[2]pyridylmethyl ester 
• 1007-49-4 2-pyridylmethyl acetate 
• 66310-15-4 pyridin-2-ylmethyl benzoate 
• 104294-19-1 pyridin-2-ylmethoxybenzene 
• 70415-71-3 4-nitrobenzoic acid 2-pyridinylmethyl ester 
• 169888-58-8 [1,2,3]Triazolo[1,5-a]pyridine-7-carbaldehyde 
• 82315-66-0 2-bromo-6-(dibromomethyl) pyridine 
• 107465-26-9 7-bromo-[1,2,3]triazolo[1,5-a]pyridine 
• 77333-83-6 2-(dibromomethyl)pyridine 
• 4377-35-9 α,α-dichloropicoline 
• 586-98-1 2-Hydroxymethylpyridine 

Relevant articles and documents

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Synthesis of novel triazolopyridylboronic acids and esters. Study of potential application to Suzuki-type reactions

This paper describes a general method for the synthesis of novel [1,2,3]triazolo[1,5-a]pyridylboronic acids and esters, and the first results on Suzuki cross-coupling reactions with these new compounds and [1,2,3]triazolo[5,1-a]isoquinolylboronic acid, re

Triazolopyridazine derivative as well as preparation method, pharmaceutical composition and application thereof

The invention relates to triazolopyridazine derivatives as well as a preparation method, a pharmaceutical composition and application thereof. The invention provides a compound shown in a general formula (I), cis-trans isomers, enantiomers, diastereoisomers, racemes, solvates, hydrates or pharmaceutically acceptable salts or prodrugs of the compound, and a preparation method of the compound, the cis-trans isomers, the enantiomers, the diastereoisomers, the racemes, the solvates, the hydrates or the pharmaceutically acceptable salts or the prodrugs of the compound; preparation method thereof; pharmaceutical compositions containing the compounds, and the use of the compounds as alpha 5-GABAA receptor modulators, wherein R 1, R 2, and Z are as defined in the specification. pharmaceutical compositions containing the compounds and application of the compounds as alpha-5-GABAA receptor modulators, wherein R1, R2 and Z are as defined in the specification.

Nitrous oxide as a diazo transfer reagent: The synthesis of triazolopyridines

Nitrous oxide is a potential diazo transfer reagent, but its applications in organic chemistry are scarce. Here, we show that triazolopyridines and triazoloquinolines are formed in the reactions of metallated 2-alkylpyridines or 2-alkylquinolines with N2O. The reactions can be performed under mild conditions and give synthetically interesting triazoles in moderate to good yields.