77144-75-3

Upstream product

• 108-24-7 acetic anhydride 
• 77144-74-2 DL-Tri-O-acetyl-1,7-O-benzylidene-(1,3,4/2,5,6)-4-azido-6-(hydroxymethyl)-1,2,3,5-cyclohexanetetrol 
• 77144-67-3 DL-(1,3/2,4)-4-(hydroxymethyl)-5-cyclohexene-1,2,3-triol 
• 70838-35-6 DL-(1,3/2,4,6)-1,2,3-tri-O-acetyl-4-bromo-6-bromomethyl-1,2,3-cyclohexanetriol 
• 77144-72-0 (1SR,3SR,6RS,8SR,9SR,10SR)-9,10-diacetoxy-3-phenyl-2,4-dioxabicyclo[4.4.0]dec-7-ene 
• 77144-65-1 DL-O-triacetyl-(1,3/2,4)-4-<(benzoyloxy)methyl>-5-cyclohexene-1,2,3-triol 
• 77144-73-1 5,7-O-benzylidene derivative of DL-3,4-di-O-acetyl-1,2-anhydro-(1,2,4,6/3,5)-1,2,3,4,5-pentahydroxy-6-hydroxymethylcyclohexane 
• 1125-88-8 benzaldehyde dimethyl acetal 
• 77144-73-1 DL-3,4-di-O-acetyl-1,2-anhydro-5,7-O-benzylidene-(1,2,4,6/3,5)-6-hydroxymethyl-1,2,3,4,5-cyclohexanepentol 
• 77144-72-0 Acetic acid (4aR,7S,8S,8aR)-7-acetoxy-2-phenyl-4a,7,8,8a-tetrahydro-4H-benzo[1,3]dioxin-8-yl ester 
• 77144-71-9 (+/-)-(4aα,7α,8aβ,8β)-2-phenyl-4a,7,8,8a-tetrahydro-4H-1,3-benzodioxin-7,8-diol 

Downstream Products

• 77144-64-0 DL-Pentaacetylhydroxyvalidamine 
• 33034-94-5 (1S,2R,3R,4R,5S,6R)-4-Amino-6-hydroxymethyl-cyclohexane-1,2,3,5-tetraol 

Relevant academic research and scientific papers

Synthetic Studies on the Validamycins. 5. Synthesis of DL-Hydroxyvalidamine and DL-Valienamine

A first synthesis of the peracetyl racemate (25) of hydroxyvalidamine (3), one of the degradation products of antibiotic validamycin B (1), is reported.The present result fully confirmed the proposed structure of 3.The sequence of reactions involves stere

SYNTHESIS OF HEXA-N,O-ACETYL-DL-HYDROXYVALIDAMINE

DL-(1,3,4/2,5,6)-4-amino-6-hydroxymethyl-1,2,3,5-cyclohexanetetrol (DL-hydroxyvalidamine) was first synthesized as the peracetate, which confirmed the proposed structure of the branched-chain aminocyclitol derived by hydrogenolysis of antibiotic validamyc