77149-03-2Relevant academic research and scientific papers
Sulfur-containing unipolar head-based double hydrophobic chain pyridine quaternary ammonium salt compounds and application thereof
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Paragraph 0072-0075, (2018/01/04)
The invention relates to the field of antibacterial agents, in particular to sulfur-containing unipolar head-based double hydrophobic chain pyridine quaternary ammonium salt compounds. A structural formula of the sulfur-containing unipolar head-based double hydrophobic chain pyridine quaternary ammonium salt compounds is shown in a formula I. The quaternary ammonium salt compounds disclosed by the invention, which can be used as a bactericide, are applied to in-can preservation of emulsion paint. The novel sulfur-containing unipolar head-based double hydrophobic chain pyridine quaternary ammonium salt compounds are synthesized, have a good antibacterial property and can be applied to the in-can preservation of the emulsion paint as the green and environment-friendly bactericide. (The formula is shown in the description).
Anti-ulcer and gastric antisecretory activity of a series of thioethers and related sulphoxides
Beattie,Crossley,Dickinson,Dover
, p. 277 - 285 (2007/10/02)
A series of thioethers containing a pyridinium moiety were prepared and tested for gastric antisecretory and anti-ulcer activity. Following initial screening two compounds 2-(3-chlorobenzylthio)-1-methylpyridinium chloride and 2-(2-fluorobenzylthio)-1-methylpyridinium chloride were investigated further. By modification of substituent groups some separation of anti-ulcer and antisecretory activity was achieved. Subsequently it was found that the pyridinium moiety could be replaced and a number of related thioethers and sulphoxides were synthesised and were also found to be active. A wide range of structural variations were found to be possible with retention of activity.
Treatment of ulcers and hypertension
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, (2008/06/13)
The invention concerns the treatment of ulcers and hypersecretion in a mammal using compounds of the formula I where Ar is phenyl, which may be substituted or cycloalkyl of 5 to 7 carbon atoms, A is saturated or unsaturated lower alkylene which may be
