77149-75-8Relevant academic research and scientific papers
rel-(1R,4R,5S)-5-HYDROXY-3-OXO-2-AZABICYCLOHEXANE, A STABLE SYNTHETIC EQUIVALENT OF 4-(2-OXOETHYL)AZETIDIN-2-ONE
Katagiri, Nobuya,Sato, Masayuki,Naito, Toshihiko,Muto, Makoto,Sakamoto, Toshiyuki,et al.
, p. 5665 - 5668 (1984)
The title compound, a synthetic equivalent of 4-(2-oxoethyl)-azetidin-2-one, has been synthesized as a stable crystalline solid either from 4-(t-butyldimethylsilyloxy)- or 4-benzyloxy-2-pyridone via photopyridone formation, catalytic hydrogenation, and de
Crystal engineering for absolute asymmetric synthesis through the use of meta substituted aryl groups
Wu, Lian-Chung,Cheer, Clair J.,Olovsson, Gunnar,Scheffer, John R.,Trotter, James,Wang, Sue-Lein,Liao, Fen-Ling
, p. 3135 - 3138 (2007/10/03)
A significant tendency towards crystallization in chiral space groups has been found for 4-benzyloxy-2-pyridones whose phenyl groups are meta-substituted (m-Cl, m-Br, m-Me and m-OMe). Irradiation of single crystals of three of these materials leads to optically active p-lactam derivatives in high chemical and optical yields via an allowed disrotatory electrocyclization.
Syntheses and Ring-opening Reactions of 5-Alkoxy- and 5-Acetoxy-3-oxo-2-azabicyclohex-5-enes
Kaneko, Chikara,Shiba, Kazuhiro,Fujii, Harure,Momose, Yu
, p. 1177 - 1178 (2007/10/02)
The efficient photochemical synthesis of 5-alkoxy- and 5-acetoxy-3-oxo-2-azabicyclohex-5-enes (2a-e and f, g), and a new rearrangement reaction of the former compounds (2a-e) to 6-alkoxy-2-pyridones (3a-e), are reported.
