77152-88-6

Basic information

• Product Name: (1E)-3-aminopropanimidamide
• CAS NO: 77152-88-6
• Molecular Formula: 2BrH*C₃H₉N₃
• Molecular Weight: 87.1237
• Mol File: 77152-88-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 182.5°C at 760 mmHg
• Flash Point: 64.2°C
• Density: 1.23g/cm³
• Vapor Pressure: 0.809mmHg at 25°C
• Refractive Index: 1.539
• CAS DataBase Reference: (1E)-3-aminopropanimidamide(CAS DataBase Reference)
• NIST Chemistry Reference: (1E)-3-aminopropanimidamide(77152-88-6)
• EPA Substance Registry System: (1E)-3-aminopropanimidamide(77152-88-6)

Safety Data

• Hazardous Substances Data: 77152-88-6(Hazardous Substances Data)

Usage

General Description

"(1E)-3-aminopropanimidamide" is a chemical compound with the molecular formula C4H11N3. It is an imidamide derivative and consists of a 3-aminopropanimidamide functional group. The compound is an organic base and likely to possess basic properties. Due to its structure, it may have potential applications in various chemical and pharmaceutical processes, including as a building block for the synthesis of other organic compounds. The exact uses and properties of this chemical may vary depending on its specific application and manufacturing process.

Upstream product

• 91977-72-9 3-(p-toluenesulfonylamino)-propionamidine 

Downstream Products

• 6576-51-8 distamycin A hydrochloride 
• 107164-67-0 C₂₃H₂₉N₉O₄*BrH 
• 85407-04-1 C₂₅H₃₃N₉O₄ 
• 85406-98-0 C₂₃H₂₉N₉O₄ 
• 85407-00-7 C₂₃H₂₉N₉O₄ 
• 85407-02-9 C₂₃H₂₉N₉O₄ 
• 85407-08-5 C₂₁H₂₅N₉O₄ 
• 85407-10-9 C₂₁H₂₅N₉O₄ 

Relevant articles and documents

Asymmetric total synthesis of sperabillins B and D via lithium amide conjugate addition

Diastereoselective conjugate addition of homochiral lithium (R)-N-allyl-N-α-methylbenzylamide to methyl (2E,5E)-hepatadienoate, followed by protecting group manipulation and subsequent iodocyclocarbamation allows a concise route to the core fragment, methyl (3R,5R,6R)-3,6-diamino-5- hydroxyheptanoate, of sperabillins B and D. Differentiation between the C-3 and C-6 primary amino groups of this core amino acid was readily achieved by treatment with acetone, giving the 5,6-isopropylidene and C-3-imine protected diamine, with subsequent regioselective acylation of the C-6-nitrogen facilitating the total synthesis of sperabillin D in 10.8% overall yield, and the first asymmetric synthesis of sperabillin B in 5.8% overall yield.