77177-16-3

Usage

Uses

Used in Pharmaceutical Industry:
(1-Benzyl-1H-1,2,3-triazol-5-yl)Methanol is used as an intermediate in the synthesis of pharmaceuticals for its unique properties and potential applications in drug discovery and development.
Used in Agrochemical Industry:
(1-Benzyl-1H-1,2,3-triazol-5-yl)Methanol is used as an intermediate in the synthesis of agrochemicals, contributing to the development of new and effective compounds for agricultural applications.
Used in Organic Compounds Synthesis:
(1-Benzyl-1H-1,2,3-triazol-5-yl)Methanol is used as a versatile building block in the synthesis of various organic compounds, enhancing reactivity and solubility in organic solvents.

Upstream product

• 107-19-7 propargyl alcohol 
• 622-79-7 benzyl azide 
• 133735-82-7 1-benzyl-5-(diethoxymethyl)-1H-1,2,3-triazole 
• 139454-85-6 1-benzyl-1,2,3-triazole-5-carbaldehyde 
• 41411-59-0 3-(toluene-4-sulfonyl)-allyl alcohol 
• 100-39-0 benzyl bromide 
• 139029-46-2 3-benzyl-3H-[1,2,3]triazole-4-carboxylic acid ethyl ester 

Downstream Products

• 139454-85-6 1-benzyl-1,2,3-triazole-5-carbaldehyde 

Relevant academic research and scientific papers

GOLD (I)-PHOSPHINE 1,2,3-TRIAZOLE DERIVATIVES WITH ANTIOBIOTIC PROPERTIES

The present invention relates to gold (l)-phosphine 1,2,3-triazole compounds, and their use in a human or animal medicine. The present invention also relates to using such compounds for the prevention and/or treatment of an infection, i.e. inhibitors of growth of Gram-positive and/or Gram-negative bacteria. On another aspect the invention relates to the synthesis of the gold (l)-phosphine compounds of the invention and to their synthesis intermediates. The present invention finds applications in the medical, veterinary and/or chemical fields.

Investigation of copper-free alkyne/azide 1,3-dipolar cycloadditions using microwave irradiation

The prevalence of 1,3-dipolar cycloadditions of azides and alkynes within both biology and chemistry highlights the utility of these reactions. However, the use of a copper catalyst can be prohibitive to some applications. Consequently, we have optimized

A general route to 1,5-disubstituted 1,2,3-triazoles with alkyl/alkyl, alkyl/aryl, aryl/aryl combinations: A metal-free, regioselective, one-pot three component approach

An experimentally simple one-pot reaction, affording 1,5-disubstituted 1H-1,2,3-triazoles in good to excellent yields by combining vinyl sulfones, sodium azide and alkyl bromides, -tosylates, -mesylates or aryl amines, -iodides is reported. The organic az

15N NMR spectroscopic and theoretical GIAO-DFT studies for the unambiguous characterization of disubstituted 1,2,3-triazoles

The 1,2,3-triazole ring has recently attracted a renewed interest as a structural scaffold with many applications in different fields. However, very often, the unambiguous assignment of the correct structure is not an easy task, and the development of rob

Method for assigning structure of 1,2,3-triazoles

1,4-Disubstituted-1H-1,2,3-triazoles 1 can easily be distinguished from the isomeric 1,5-disubstituted-1H-1,2,3-triazoles 2 by simple one-dimensional 13C NMR spectroscopy using gated decoupling. The C5 signal of 1 appears at δ ～120 p

Non-magnetic and magnetic supported copper(I) chelating adsorbents as efficient heterogeneous catalysts and copper scavengers for click chemistry

Novel supported chelating adsorbents bearing diverse multidentate nitrogenated ligands with strong copper(I) affinities are easily prepared in non-magnetic and magnetic variants using silica and silica-coated magnetite nanoparticles as suitable supports a

DIAZEPANES AS HISTAMINE H3 RECEPTOR ANTAGONISTS

The invention relates to compounds of formula (I) wherein R1 to R8 and X1, X2 have the meaning as cited in the description and the claims. Said compounds are useful as Histamine H3 receptor antagonists. The invention also relates to pharmaceutical compositions, the preparation of such compounds as well as the production and use as medicament.

CYCLOADDITION OF FUNCTIONALLY SUBSTITUTED AZIDES TO ACETYLENIC ALCOHOLS

The corresponding hydroxymethyl-1,2,3-triazoles were obtained by the reaction of monosubstituted and disubstituted acetylenic alcohols with a wide range of organic azides.It was shown that the reaction of azidoacetic acid with acetylenic keto alcohols is accompanied by the formation of triazolooxazines; sterically hindered azides do not add to the acetylenic carbinols; azido ketones are converted in the reaction into urethane and carbanilide.