77180-87-1

Basic information

• Product Name: 2',3'-di-O-benzoyl-5'-deoxy-5-fluorouridine
• Synonyms: 2',3'-di-O-benzoyl-5'-deoxy-5-fluorouridine
• CAS NO: 77180-87-1
• Molecular Weight: 454.411
• Mol File: 77180-87-1.mol

Chemical Properties

• CAS DataBase Reference: 2',3'-di-O-benzoyl-5'-deoxy-5-fluorouridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2',3'-di-O-benzoyl-5'-deoxy-5-fluorouridine(77180-87-1)
• EPA Substance Registry System: 2',3'-di-O-benzoyl-5'-deoxy-5-fluorouridine(77180-87-1)

Safety Data

• Hazardous Substances Data: 77180-87-1(Hazardous Substances Data)

Upstream product

• 15958-99-3 5'-deoxyuridine 
• 98-88-4 benzoyl chloride 
• 69260-71-5 doxifluridine 
• 51-21-8 5-fluorouracil 
• 151378-79-9 methyl 5-deoxy-2,3-di-O-benzoyl-D-ribofuranoside 

Downstream Products

• 69260-71-5 doxifluridine 

Relevant articles and documents

Uracil nucleoside derivative and method for preparing deoxyuridine drug by using same (by machine translation)

The invention discloses (I) deoxy - D D-furan ribose 5 - styryl 1 - [2 - (1 - benzoate) derivative represented by the formula] and a preparation method, of the derivative, wherein the structure of the general formula (I) is shown. And the preparation method (I) of, deoxy - D D-furan ribose 5 - styryl 1 - [2 - (1 - benzoate) derivatives as above reaction raw materials can be used as a glycosyl donor to activate] under the conditions of the catalytic amount of the Lewis acid trifluoromethanesulfonate and N - iodosuccinimide, and, reaction efficient, yield 98%. reaching, is avoided in the conventional reaction system using an equivalent or excess of a Lewis acid, benzoyldiimide as a glycosyl donor. (by machine translation)

Fluorocytidine derivatives

The novel 5'-deoxy-5-fluorocytidine derivatives of formula STR1 wherein R1, R2 and R3 are hydrogen or an easily hydrolyzable radical under physiological conditions, with the proviso that, at least one or R1, Rs