77185-78-5 Usage
Uses
Used in Organic Synthesis:
ETHYL 3,5-DIBROMO-1H-INDOLE-2-CARBOXYLATE is used as a reagent in organic synthesis for its ability to participate in cross-coupling reactions. The presence of two bromine atoms in its structure makes it a versatile building block for the creation of various organic compounds and molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, ETHYL 3,5-DIBROMO-1H-INDOLE-2-CARBOXYLATE is used as a starting material or intermediate in the synthesis of potential drug candidates. Its unique structure and reactivity contribute to the development of new therapeutic agents with specific biological activities.
Used in Chemical Research:
ETHYL 3,5-DIBROMO-1H-INDOLE-2-CARBOXYLATE is also used in chemical research as a model compound to study various reaction mechanisms and to develop new synthetic methodologies. Its reactivity and structural features make it an interesting subject for academic and industrial research.
Used in Material Science:
In the field of material science, ETHYL 3,5-DIBROMO-1H-INDOLE-2-CARBOXYLATE may be used as a component in the development of new materials with specific properties, such as optoelectronic materials or functional polymers. Its chemical structure and reactivity can be exploited to create materials with tailored characteristics for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 77185-78-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,1,8 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 77185-78:
(7*7)+(6*7)+(5*1)+(4*8)+(3*5)+(2*7)+(1*8)=165
165 % 10 = 5
So 77185-78-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H9Br2NO2/c1-2-16-11(15)10-9(13)7-5-6(12)3-4-8(7)14-10/h3-5,14H,2H2,1H3
77185-78-5Relevant academic research and scientific papers
Synthesis of Substituted 7,12-Dihydroindolo-benzodiazepin-5(6H)-ones and 1,2,3,4,5,6-Hexahydro-diazepinoindole-1,5-diones
Hiremath, Shivayogi P.,Badami, Prema S.,Purohit, Muralidhar G.
, p. 1058 - 1063 (2007/10/02)
The title compounds (10 and 18) have been synthesised through a series of reactions.Bromination (Br2/AcOH) of ethyl indole-2-carboxylates (1a-e) and subsequent treatment of the resultant 3-bromo derivatives (2a-e) with hydrazine hydrate (80percent) in eth
Synthesis of Substituted Indolobenzodiazepine Derivatives
Hiremath, Shivayogi P.,Hiremath, Dakshayani M.,Purohit, Muralidhar G.
, p. 930 - 933 (2007/10/02)
Various substituted-7,12-dihydroindolobenzodiazepines (4a-e) have been prepared from the corresponding 3-aminoindoles (1a-e) through Ullmann reaction with o-chloroaniline, acylation of the resulting 3-(o-aminophenylamino)indoles (2a-e) and cyclization of amides (3a-e) with POCl3.Similar systems have also been synthesized from ethyl 3-bromoindole-2-carboxylates (6a-e).The bromo esters react with o-phenylenediamine to give ethyl 3-(o-aminophenylamino)indole-2-carboxylates (7a-e) which undergo cyclization in the presence of PPA to yield 5,6,7,12-tetrahydroindolobenzodiazepin-6-ones (8a-e).
