77185-78-5 Usage
General Description
ETHYL 3,5-DIBROMO-1H-INDOLE-2-CARBOXYLATE is a chemical compound belonging to the group of indole carboxylic acids and derivatives. Its molecular formula is C11H8Br2NO2 and it is commonly used in organic synthesis. The presence of two bromine atoms makes it a useful reagent for cross-coupling reactions. In addition to its use in synthesis, this compound is studied for potential biological activities. As with most chemical substances, precautions should be taken to avoid skin and eye contact, inhalation or ingestion. It is typically available as a solid and should be stored in a cool, dry place.
Check Digit Verification of cas no
The CAS Registry Mumber 77185-78-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,1,8 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 77185-78:
(7*7)+(6*7)+(5*1)+(4*8)+(3*5)+(2*7)+(1*8)=165
165 % 10 = 5
So 77185-78-5 is a valid CAS Registry Number.
InChI:InChI=1/C11H9Br2NO2/c1-2-16-11(15)10-9(13)7-5-6(12)3-4-8(7)14-10/h3-5,14H,2H2,1H3
77185-78-5Relevant articles and documents
Synthesis of Substituted 7,12-Dihydroindolo-benzodiazepin-5(6H)-ones and 1,2,3,4,5,6-Hexahydro-diazepinoindole-1,5-diones
Hiremath, Shivayogi P.,Badami, Prema S.,Purohit, Muralidhar G.
, p. 1058 - 1063 (2007/10/02)
The title compounds (10 and 18) have been synthesised through a series of reactions.Bromination (Br2/AcOH) of ethyl indole-2-carboxylates (1a-e) and subsequent treatment of the resultant 3-bromo derivatives (2a-e) with hydrazine hydrate (80percent) in eth