77204-01-4 Usage
Chemical structure
3-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]-2-(2-hydroxyphenyl)-1,3-thiazolidin-4-one consists of a thiazole ring and a thiazolidinone ring as its core structure.
Functional groups
The compound contains a chlorophenyl group (4-chlorophenyl) and a hydroxyphenyl group (2-hydroxyphenyl) attached to the thiazole and thiazolidinone rings, respectively.
Aromatic character
The presence of the phenyl ring in both chlorophenyl and hydroxyphenyl groups indicates that the compound has aromatic character, which may contribute to its biological activity.
Halogen presence
The chlorine atom in the chlorophenyl group may affect the compound's lipophilicity and ability to interact with biological targets.
Hydrophilic property
The hydroxyl group (-OH) in the hydroxyphenyl group imparts hydrophilic properties to the compound, which can influence its solubility and interactions with polar biological molecules.
Potential biological activity
The unique structural features of the compound, including the presence of thiazole and thiazolidinone rings, as well as the chlorophenyl and hydroxyphenyl groups, may contribute to its potential biological activity.
Interest in pharmaceutical and medicinal chemistry
Due to its structural features and potential biological activity, this compound may be of interest for further research in the development of new drugs and therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 77204-01-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,2,0 and 4 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 77204-01:
(7*7)+(6*7)+(5*2)+(4*0)+(3*4)+(2*0)+(1*1)=114
114 % 10 = 4
So 77204-01-4 is a valid CAS Registry Number.
77204-01-4Relevant articles and documents
Synthesis and Biological Activity of Some Schiff Bases Derived from Thiazoles and Benzothiazoles
Dash, B.,Patra, M.,Praharaj, S.
, p. 894 - 897 (2007/10/02)
4-Aryl-2-aminothiazoles and 2-aminobenzothiazoles undergo condensation with salicylaldehyde in the presence of piperidine to give the schiff bases II and III, respectively.A similar reaction of 4-aryl-2-aminothiazole methiodides gives the schiff bases 4-aryl-2-(2'-hydroxyaryliminomethyl)thiazole methiodides (IV).Several schiff bases have been condensed with cyclohexanone and thioglycollic acid to furnish 4-aryl-2-(2'-hydroxy-α-substituted benzylamino)thiazoles (V) and 2-(2'-hydroxyphenyl) or naphthyl)-3-(4''-arylthiazol-2''-yl)-4-thiazolidones (VI), respectively.Structure elucidation of the schiff bases has been made on the basis of their elemental analyses, IR and mass spectral data.The biological screening data of the schiff bases and their metal complexes are also presented.
