77206-76-9Relevant academic research and scientific papers
Antihypertensive Activity of 6-Arylpyridopyrimidin-7-amine Derivatives. 2. 7-Acyl Amide Analogues
Blankley, C. John,Bennett, Lawrence R.,Fleming, Robert W.,Smith, Ronald D.,Tessman, Deirdre K.,Kaplan, Harvey R.
, p. 403 - 411 (2007/10/02)
The effect of acylation with a variety of acids on the antihypertensive activity of 6-(2,6-dichlorophenyl)pyridopyrimidin-7-amine (1) is reported, and structure-activity relationships are discussed.Although several of the compounds show good oral a
6-Substituted-arylpyrido[2,3-d]pyrimidin-7-amines and derivatives
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, (2008/06/13)
6-Substituted-arylpyrido[2,3-d]pyrimidin-7-amines and derivatives and their pharmaceutically acceptable acid addition salts are useful in the treatment of hypertension.
