77207-93-3

Upstream product

• 5362-72-1 3-pentanone tosylhydrazone 

Downstream Products

• 101055-94-1 2-(2,4-Dioxo-3-phenyl-1,3,5-triaza-bicyclo[3.2.0]hept-6-yl)-3-methyl-6-phenyl-[1,2,4]triazolo[1,2-b][1,2,3]thiadiazole-5,7-dione 
• 101055-98-5 8-Methyl-2,6-diphenyl-3b,4-dihydro-9-thia-2,3a,4a,6,7a,9a-hexaaza-cyclopenta[a]-s-indacene-1,3,5,7-tetraone 

Relevant academic research and scientific papers

Die Regioselektivitaet der Ringschlussreaktionen zu 1,2,3-Thiadiazolen und 1,2,3-Selenadiazolen

Unsymmetrical hydrazones of type 2 exist in a Z/E-equilibrium from which ring closure reactions with SOCl2 or SeO(OH)2 occur.Isomeric 1,2,3-thiadiazoles 3/3' and 1,2,3-selenadiazoles 4/4', respectively, are formed.Regioselectivities are discussed concerning the examples 2a - t.For b, c, d, and o product distributions are rationalized on the basis of the Z/E-equilibrium proportions and the ratio of reactivities.Principally, methylene hydrogens are more reactive than methyl hydrogens, even when the reaction on the methyl side predominates.