77213-50-4Relevant academic research and scientific papers
Alkylation et acetylation d'acridanones. Cas de la methoxy-2 acridanone-9
Chaffia, Brat Ali,Montginoul, Claude,Toreilles, Eliane,Giral, Louis
, p. 345 - 350 (2007/10/02)
The interest of the N-alkylacridanone derivatives lies in their biological properties.We describe the results of various substitution reactions of 2-methoxy-9-acridanone.This substrate, previously metallated by sodium hydride, was reacted with alkyl, allyl, crotyl and benzyl halides and also with alkylamino and acetyl halides in dimethylformamide.A mixture of O-alkyl and N-alkyl isomers, or only one of them, was obtained.The reaction products are interpreted in terms of hardness and softness of reacting centres.
