77222-65-2Relevant articles and documents
On the Nature of 'Haematoporphyrin Derivative'
Bonnett, Raymond,Ridge, Richard J.,Scourides, Panayiotis A.,Berenbaum, Morris C.
, p. 3135 - 3140 (2007/10/02)
The components of haematoporphyrin derivative ( a preparation used as a photosensitiser in clinical applications, and made by treating haematoporphyrin with sulphuric acid-acetic acid) have been separated by preparative h.p.l.c. and identified by comparison with authentic porphyrincarboxylic acids.The composition of the mixture is somewhat variable but the main components are O,O'-diacetylhaematoporphyrin (6) and O-acetylhaematoporphyrin (2)/(3) with smaller amounts of the 8(3)-(1-acetoxyethyl)-3(8)-vinyldeuteroporphyrin isomers (7) and (8) and the corresponding alcohols (4) and (5).