772283-93-9 Usage
Uses
Used in Pharmaceutical Industry:
4-Piperidinecarboxylic acid, 4-(phenylamino)is used as an intermediate in the synthesis of Remifentanil Ester Hydrochloride (R143515), a controlled substance and an opioid. It plays a crucial role in the production of this potent analgesic, which is used for pain management in various medical settings.
Additionally, 4-Piperidinecarboxylic acid, 4-(phenylamino)is used as an intermediate in the synthesis of isothiocyanate derivatives of carfentanils and (methoxymethyl)fentanyls. These compounds are opioid δ receptor irreversible inhibitors, which have potential applications in the development of new therapeutic agents for the treatment of opioid addiction and related disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 772283-93-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,7,2,2,8 and 3 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 772283-93:
(8*7)+(7*7)+(6*2)+(5*2)+(4*8)+(3*3)+(2*9)+(1*3)=189
189 % 10 = 9
So 772283-93-9 is a valid CAS Registry Number.
772283-93-9Relevant academic research and scientific papers
PROCESS FOR SYNTHESIZING REMIFENTANIL
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Page/Page column 23, (2008/06/13)
A process for synthesizing remifentanil or carfentanil, as well as intermediates for use in the preparation of synthetic opiate or opioid compounds. The process comprising reacting a 4-amino 4-carbamyl piperidine with a base in a closed reaction chamber at elevated temperature and pressure to form to intermediate which may be esterified with an alcohol, alkylated, and acylated to produce a synthetic opiate or opioid compound.