77246-56-1Relevant academic research and scientific papers
Synthesis of tetrasubstituted NH pyrroles and polysubstituted furans via an addition and cyclization strategy
Li, Liang,Zhao, Mi-Na,Ren, Zhi-Hui,Li, Jianli,Guan, Zheng-Hui
experimental part, p. 532 - 540 (2012/04/04)
The FeCl3-catalyzed addition and cyclization of enamino esters with nitroolefins provides a straightforward and general method for the synthesis of tetrasubstituted NH pyrroles. This novel method tolerates a wide range of functionality, and allows for rapid elaboration of the nitroolefins into a variety of substituted pyrroles in good yields. Further, an efficient KOAc-promoted addition and cyclization protocol toward substituted furans has been described as well. Georg Thieme Verlag Stuttgart · New York.
A mild and efficient method for the synthesis of vinylogous carbamates from alkyl azides
Reddy, D. Srinivasa,Rajale, Trideep V.,Shivakumar,Iqbal, Javed
, p. 979 - 982 (2007/10/03)
A mild and efficient one-pot method for the synthesis of vinylogous carbamates is reported starting from alkyl azides under a hydrogen atmosphere using 10% Pd/C. The resulting products are useful intermediates for the synthesis of heterocyclic compounds, natural products, and in peptidomimetics.
Unusual Michael Reaction of Acyclic 1,3-Dicarbonyl Compounds with Nitro-olefins. A Novel Pyrrole Synthesis
Gomez-Sanchez, Antonio,Stiefel, Berta Marco,Fernandez-Fernandez, Rosario,Pascual, Conrado,Bellanato, Juana
, p. 441 - 447 (2007/10/02)
Acetoacetic esters and pentane-2,4-dione undergo unusual Michael reactions with β-nitrostyrene in methanol-sodium methoxide to form the (2R,3R,2'S,3'S)-bis-(4-acyl-2,3-dihydro-5-methyl-3-phenyl-2)-furylhydroxylamines (5) in high yields.The normal adducts
