77249-70-8Relevant academic research and scientific papers
Cyclic Urea Nucleosides. Cytidine Deaminase Activity as a Function of Aglycon Ring Size
Liu, Paul S.,Marquez, Victor E.,Driscoll, John S.,Fuller, Richard W.,McCormack, John J.
, p. 662 - 666 (2007/10/02)
Five β-D-ribofuranosyl cyclic urea nucleosides (14-18), ranging in size from five to eight membered, were synthesized and evaluated as cytidine deaminase (CDA) inhibitors.The precursor protected nucleosides (9-13) were prepared by a condensation procedure
Seven-membered ring compounds as inhibitors of cytidine deaminase
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, (2008/06/13)
Seven-membered heterocyclic nucleosides used to inhibit the deamination enzyme responsible for the inactivation of arabinosylcytosine (ara--C). Preferred nucleosides containing a seven-member aglycone are as follows: STR1 Preferred aglycones are as follow
