7728-74-7 Usage
General Description
2-(thiazol-4-yl)ethylamine is a chemical compound with the molecular formula C6H10N2S. It is a derivative of thiazole, a heterocyclic compound containing both sulfur and nitrogen atoms in its five-membered ring structure. 2-(THIAZOL-4-YL)ETHYLAMINE is used as a building block in organic synthesis and medicinal chemistry, particularly in the design and development of pharmaceuticals and agrochemicals. It is also known for its potential application in the field of materials science and as a ligand in coordination chemistry. The properties and reactivity of 2-(thiazol-4-yl)ethylamine make it a versatile and valuable chemical for various research and industrial applications.
Check Digit Verification of cas no
The CAS Registry Mumber 7728-74-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,7,2 and 8 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7728-74:
(6*7)+(5*7)+(4*2)+(3*8)+(2*7)+(1*4)=127
127 % 10 = 7
So 7728-74-7 is a valid CAS Registry Number.
InChI:InChI=1/C5H8N2S/c6-2-1-5-3-8-4-7-5/h3-4H,1-2,6H2
7728-74-7Relevant articles and documents
INDANE DERIVATES AS MUSCARINIC RECEPTOR AGONISTS
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Page 40, (2010/02/10)
The present invention relates to compounds of Formula I: I which are agonists of the M-1 muscarinic receptor.
Histamine H1 receptor ligands. Part I. Novel thiazol-4-ylethanamine derivatives: Synthesis and in vitro pharmacology
Walczynski,Timmerman,Zuiderveld,Zhang,Glinka
, p. 533 - 541 (2007/10/03)
A series of 2-substituted thiazol-4-ylethanamines have been synthesized and tested for their histaminergic H1-receptor activities. The compounds with 2-phenyl substitution, regardless of the different physicochemical properties of the meta-substituents at the phenyl ring, showed weak H1-agonistic activity with pD2 values ranging from 4.35 to 5.36. When the phenyl group was replaced by a benzyl group, the resulting compounds all exhibited weak H1-antagonistic activity (pA2: 4.14-4.82). Copyright (C) 1999 Elsevier Science S.A.
