773012-60-5

Usage

Chemical classification

Cycloalkylamine derivative

Structural components

A phenyl group attached to a cyclopropyl ring

Potential pharmaceutical properties

Has been studied for its potential as a therapeutic agent for various medical conditions

Applications

May have applications in the field of medicinal chemistry and drug development

Need for further research

Further research is needed to fully understand its potential uses and effects.

Upstream product

• 557-20-0 diethylzinc 
• 100-47-0 benzonitrile 

Downstream Products

• 73930-39-9 1-phenylcyclopropane-1-amine hydrochloride 
• 1598426-03-9 ethyl 2-((1-phenylcyclopropyl)amino)pyrimidine-5-carboxylate 
• 1375465-91-0 N-hydroxy-2-((1-phenylcyclopropyl)amino)pyrimidine-5-carboxamide 
• 1314495-37-8 4,4,5,5-tetramethyl-2-(1-phenylcyclopropyl)-1,3,2-dioxaborolane 
• 1439556-98-5 C₃₇H₃₈N₆O₃S 
• 1422208-41-0 C₂₄H₃₂N₂O₃ 
• 1245647-91-9 C₁₃H₁₈N₂ 

Relevant academic research and scientific papers

Primary 1-Arylcyclopropylamines from aryl cyanides with diethylzinc and titanium alkoxides

(Matrix presented) 1-Aryl-substituted primary cyclopropylamines are conveniently prepared from aromatic nitriles and diethylzinc. The yields range from 40 to 56% for donor-substituted (five examples) to 62-82% for non- and acceptor-substituted substrates

THIADIAZOLEDIOXIDES AND THIADIAZOLEOXIDES AS CXC- AND CC-CHEMOKINE RECEPTOR LIGANDS

Disclosed are novel compounds of the formula (IA) and the pharmaceutically acceptable salts and solvates thereof. Examples of groups comprising Substituent A include heteroaryl, aryl, heterocycloalkyl, cycloalkyl, aryl, alkynyl, alkenyl, aminoalkyl, alkyl or amino. Examples of groups comprising Substituent B include aryl and heteroaryl. Also disclosed is a method of treating a chemokine mediated diseases, such as, cancer, angiogenisis, angiogenic ocular diseases, pulmonary diseases, multiple sclerosis, rheumatoid arthritis, osteoarthritis, stroke and cardiac reperfusion injury, acute pain, acute and chronic inflammatory pain, and neuropathic pain using a compound of formula (IA).

3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.

3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands

There are disclosed compounds of the formula or a pharmaceutically acceptable salt or solvate thereof which are useful for the treatment of chemokine-mediated diseases such as acute and chronic inflammatory disorders and cancer.