7731-48-8Relevant academic research and scientific papers
Visible-Light-Promoted, Catalyst-Free Gomberg-Bachmann Reaction: Synthesis of Biaryls
Lee, Juyoung,Hong, Boseok,Lee, Anna
, p. 9297 - 9306 (2019/08/12)
Biaryls were synthesized via a novel visible-light-promoted Gomberg-Bachmann reaction that does not require a photosensitizer or any metal reagents. The formation of an electron donor-acceptor complex between aryl diazonium salts and pyridine allows, under visible-light irradiation, the synthesis of biaryls in moderate-to-high yields.
Mono-arylation method of dichlorobenzene compounds
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Paragraph 0024; 0026; 0028; 0029, (2018/05/16)
A mono-arylation method of dichlorobenzene compounds comprises the steps as follows: dichlorobenzene compounds shown in formula (I), arylboronic acid shown in formula (2), a N-heterocyclic carbene-palladium complex catalyst, an alkaline substance and a reaction solvent are mixed to react at 0-100 DEG C for 1-24 h under the protection of nitrogen, a reaction solution is subjected to posttreatment,and a mono-arylation product shown in formula (3) is obtained. A novel catalytic system is developed, the catalyst is stable and easy to obtain, the stable and cheap dichlorobenzene compounds can be subjected to the selective mono-arylation reaction, and the method has multiple advantages that the reaction operation is simple, the cost is low, the product is high in yield and purity and the like,is a brand-new method for synthesizing chloro-biphenyl compounds, provides a new synthesis route for the compounds and has good research value and industrial application prospects.
