773133-85-0Relevant academic research and scientific papers
The first synthesis and cytostatic activity of novel 6-(fluoromethyl)purine bases and nucleosides
Silhar, Peter,Pohl, Radek,Votruba, Ivan,Hocek, Michal
, p. 3001 - 3007 (2007/10/03)
Two alternative approaches to the synthesis of novel 6-(fluoromethyl)purine bases and nucleosides are described either by direct deoxyfluorination or by multistep functional group transformations starting from 6-(hydroxymethyl) purines. 6-(Fluoromethyl)pu
Facile and efficient synthesis of 6-(hydroxymethyl)purines
Silhar, Peter,Pohl, Radek,Votruba, Ivan,Hocek, Michal
, p. 3225 - 3228 (2007/10/03)
(Chemical Equation Presented) A facile and efficient methodology of the synthesis of 6-(hydroxymethyl)purine derivatives (bases and nucleosides) was developed based on Pd-catalyzed cross-coupling reactions of 6-halopurines with acyloxymethylzinc iodides f
