773136-66-6Relevant academic research and scientific papers
PET probe targeting tropomyosin receptor kinase TRK fusion protein, as well as synthesis and application thereof
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Paragraph 0057-0061, (2019/07/10)
The invention relates to a PET probe targeting tropomyosin receptor kinase TRK fusion protein, as well as synthesis and application thereof. The PET probe has a molecular structure as shown in the specification. Compared with the prior art, the novel TRK
4-METHYL-2,3,5,9,9B-PENTAAZA-CYCLOPENTA[A]NAPHTHALENES
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Page/Page column 95-97, (2014/02/16)
The invention relates to 4-methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalene derivatives of general formula (I) which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.
4-Methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalenes
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Paragraph 0565-0568; 0577, (2014/03/21)
The invention relates to 4-methyl-2,3,5,9,9b-pentaaza-cyclopenta[a]naphthalene derivatives of general formula (I) which are inhibitors of phosphodiesterase 2 and/or 10, useful in treating central nervous system diseases and other diseases. In addition, the invention relates to processes for preparing pharmaceutical compositions as well as processes for manufacture the compounds according to the invention.
SUBSTITUTED SULFONAMIDES USEFUL AS ANTIAPOPTOTIC BCL INHIBITORS
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Page/Page column 173-174, (2012/12/13)
Disclosed are compounds of Formula (I), or a pharmaceutically acceptable salt thereof, wherein: W and Q and G are defined herein. Also disclosed are methods of using such compounds as inhibitors of Bcl-2 family antiapoptotic proteins for the treatment of cancer; and pharmaceutical compositions comprising such compounds.
