773148-44-0Relevant academic research and scientific papers
Jacobsen protocols for large-scale epoxidation of cyclic dienyl sulfones: Application to the (+)-pretazettine core
Ebrahimian, G. Reza,Du Jourdin, Xavier Mollat,Fuchs, Philip L.
supporting information; experimental part, p. 2630 - 2633 (2012/07/17)
A Jacobsen epoxidation protocol using H2O2 as oxidant was designed for the large-scale preparation of various epoxy vinyl sulfones. A number of cocatalysts were screened, and pH control led to increased reaction rate, higher turnover
Improved and environmentally friendly large-scale preparation of cyclohexadienyl-, cycloheptadienyl sulfone and enantiopure epoxy cycloheptyl sulfones
Park, Taesik,Torres, Eduardo,Fuchs, Philip L.
, p. 1895 - 1900 (2007/10/03)
Kilogram-scale amounts of cycloheptadienyl phenylsulfone and cyclohexadienyl phenylsulfone were prepared by one operation in 5 stages with over 50% yield and requiring no purification. A practical and efficient method for the Jacobsen asymmetric epoxidati
Synthesis of enantiopure termini-differentiated heptane stereotriads. 1 Application to side chain-functionalized tetrahydrofurans of IKD-8344
Jiang, Wanlong,Lantrip, Douglas A.,Fuchs
, p. 2181 - 2184 (2007/10/03)
(equation presented) Enantiopure epoxy cycloheptenyl sulfones syn-7b and anti-7b are prepared in five high-yielding and stereospecific operations from 1,3-cycloheptadiene. These substrates serve as effective precursors for cis- and trans-substituted tetra
