77326-37-5 Usage
Properties
Aromatic compound with a nitrile group and a methylsulfonyl substituent
Uses
Building block in synthesis of pharmaceuticals and agrochemicals, precursor for organic dyes and pigments
Applications
Potential as enzyme and receptor inhibitor for pharmaceutical development
Caution
Potential risks to human health and the environment, handle with care
Check Digit Verification of cas no
The CAS Registry Mumber 77326-37-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,3,2 and 6 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 77326-37:
(7*7)+(6*7)+(5*3)+(4*2)+(3*6)+(2*3)+(1*7)=145
145 % 10 = 5
So 77326-37-5 is a valid CAS Registry Number.
77326-37-5Relevant academic research and scientific papers
N-(Aminophenyl)oxamic Acids and Esters as Potent, Orally Active Antiallergy Agents
Klaubert, Dieter H.,Sellstedt, John H.,Guinosso, Charles J.,Capetola, Robert J.,Bell, Stanley C.
, p. 742 - 748 (2007/10/02)
A series of N-(2-cyano-substituted-phenyl)oxamates was prepared by acylation of the appropriate anthranilonitrile with ethyloxalyl chloride.Hydrolysis with sodium hydroxide gave the corresponding oxamic acid sodium salts.These compounds were extremely potent when tested in the rat passive cutaneous anaphylaxis (PCA assay either by the ip or the po route of administration).One of the sodium salts, oxoacetic acid sodium salt (11a, Wy-41 195), has ED50 value of 0.07 mg/kg po and has been selected for further evaluation.
