77332-65-1

Usage

Uses

Used in Pharmaceutical Industry:
1-bromo-5-chloronaphthalene is used as an intermediate in the synthesis of various pharmaceuticals for its high reactivity and ability to form new compounds with potential therapeutic properties.
Used in Dye Industry:
1-bromo-5-chloronaphthalene is used as a key component in the production of dyes, where its unique chemical structure contributes to the development of novel dyes with specific color characteristics and properties.
Used in Pesticide Industry:
1-bromo-5-chloronaphthalene is used as a precursor in the formulation of pesticides, leveraging its reactivity to create effective compounds for pest control and management.
Used in Organic Synthesis:
1-bromo-5-chloronaphthalene is used as a versatile building block in organic synthesis, enabling the creation of a wide range of chemical compounds for various applications across different industries.
Used in Material Development:
1-bromo-5-chloronaphthalene is used in the development of new materials and processes, taking advantage of its unique structure and reactivity to improve existing materials or create innovative ones with enhanced properties.

InChI:InChI=1/C10H6BrCl/c11-9-5-1-4-8-7(9)3-2-6-10(8)12/h1-6H

Upstream product

• 4766-33-0 5-amino-1-bromonaphthalene 
• 90-11-9 1-Bromonaphthalene 
• 10026-13-8 phosphorus pentachloride 
• 50638-04-5 5-bromnaphthalin-1-sulfochlorid 
• 42918-20-7 1-allyl-2-bromobenzene 

Downstream Products

• 5018-89-3 2-(5-chloro-[1]naphthoyl)-benzoic acid 
• 14955-98-7 o-(5-Chloro-1-naphthylmethyl)-benzoic acid 
• 14944-57-1 o-(5-Chloro-1-naphthylmethyl)-acetophenone 

Relevant academic research and scientific papers

A Visible Light and Iron-mediated Carbocationic Route to Polysubstituted 1-Halonaphthalenes by Benzannulation using Allylbenzenes and Polyhalomethanes

A wide array of polysubstituted 1-bromo and chloronaphthalenes are obtained from coupling of allylbenzenes and polyhalomethanes. The reaction is mediated by iron metal under visible light irradiation and proceeds via a Kharasch addition intermediate followed by intramolecular FeIII mediated Friedel-Crafts alkylation, with the formation of two Csp2?Csp2 bonds in the process. This method gives easy access to 1-halonaphthalenes with substituent(s) at C-5 to C-8 that are otherwise hard to synthesize. (Figure presented.).

DIHYDROIMIDAZOTHIAZOLE DERIVATIVES

Compounds of formula (I): or pharmaceutically acceptable salts thereof, exhibit 5-HT1A agonism in addition to noradrenaline reuptake inhibition and optionally also 5-HT reuptake inhibition are useful for the treatment of obesity.

The Reaction of Iodine Monochloride with Polycyclic Aromatic Compounds: Polar and Electron Transfer Pathways

Several polycyclic aromatic hydrocarbons were treated with iodine monochloride.Although iodination is the predominant reaction of benzenoid arenes, chlorination is the sole reaction with anthracene, phenanthrene and naphthalene compounds (except for 5), whose oxidation half-wave potentials are less than 1.58 V vs Ag/Ag(+) (0.1 M).Arenes with higher potentials are unreactive.Naphthalene (9) and its derivatives with mild electron-withdrawing substituents are chlorinated; the exception (5) yields the 1-iodo product (21).The reaction is first order in substrate and second order in ICl.An electron transfer pathway involving radical cation intermediates is assumed.Ion-pair collapse of the radical cation-ICl intermediates is proposed for the chlorinations and radical-pair collapse for the iodination.