42918-20-7

Basic information

• Product Name: o-Allylbromobenzene
• Synonyms: 1-Allyl-2-bromobenzene;2-Allylbromobenzene;2-Allylphenyl bromide;2-Bromo-1-allylbenzene;o-Allylbromobenzene;1-Allyl-2-bromobenzene 97%;1-bromo-2-(prop-2-enyl)benzene
• CAS NO: 42918-20-7
• Molecular Formula: C₉H₉Br
• Molecular Weight: 197.07176
• Product Categories: Aryl;Building Blocks;C9 to C12;Chemical Synthesis;Halogenated Hydrocarbons;Organic Building Blocks
• Mol File: 42918-20-7.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 52-54 °C(Press: 0.2 Torr)
• Flash Point: 93°C
• Appearance: /
• Density: 1.311g/mLat 25℃
• Refractive Index: n20/D 1.559
• Storage Temp.: 2-8°C
• CAS DataBase Reference: o-Allylbromobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: o-Allylbromobenzene(42918-20-7)
• EPA Substance Registry System: o-Allylbromobenzene(42918-20-7)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36
• Safety Statements: 26
• WGK Germany: 3
• Hazardous Substances Data: 42918-20-7(Hazardous Substances Data)

Usage

General Description

o-Allylbromobenzene is a chemical compound with the molecular formula C9H9Br. It is a clear, colorless liquid with a sweet, floral odor, and it is primarily used as an intermediate in the production of pharmaceuticals, agrochemicals, and organic compounds. It is also used in the synthesis of other chemicals and as a reagent in organic chemical reactions. In addition, o-Allylbromobenzene is considered to be a potential environmental hazard due to its high flammability and toxicity, and it requires proper handling and storage to prevent risk to human health and the environment.

Upstream product

• 106-95-6 allyl bromide 
• 615-36-1 2-bromoaniline 
• 762-72-1 allyl-trimethyl-silane 
• 10448-07-4 2-bromobenzenediazonium tetrafluoroborate 
• 593-60-2 Vinyl bromide 
• 3433-80-5 1-Bromo-2-bromomethyl-benzene 
• 583-55-1 1-Bromo-2-iodobenzene 
• 107-05-1 3-chloroprop-1-ene 
• 1826-67-1 vinyl magnesium bromide 

Downstream Products

• 77332-65-1 1-Bromo-5-chloronaphthalene 
• 372193-58-3 (2-allylphenyl)boronic acid 
• 6630-33-7 ortho-bromobenzaldehyde 
• 147298-15-5 2-(2-Propenyl)<(trimethylsilyl)ethynyl>benzene 
• 66223-53-8 trans-2-bromocinnamaldehyde 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 52221-92-8 3-(2-bromo-phenyl)-propan-1-ol 
• 177324-09-3 3-(2-bromophenyl)propyl methyl ether 

Relevant articles and documents

Bimetal Cooperatively Catalyzed Arylalkynylation of Alkynylsilanes

An unprecedented Pd/Rh cooperatively catalyzed arylalkynylation of alkynylsilanes was developed to merge an alkynylidene moiety with benzosilacycle. These silaarenes possess a particular aggregation-induced emission behavior. Mechanistic investigations demonstrate that the relay trimetallic transmetalation plays a pivotal role in governing this transformation.

Spirocyclic tetrahydroquinazolines

The invention discloses spirocyclic tetrahydroquinazolines , and particularly provide compounds represented by Formula I shown in the specification, and pharmaceutically acceptable salts and solvates thereof. In the formula, R3, A, A1, A2, A3, E, E1, E2, L, Q, Z and a structure shown in the specification are as defined in the specification,. The compounds of formula I are KRAS inhibitors and are therefore useful in the treatment of cancer and other diseases.

Cross-Coupling Reactions of Aryldiazonium Salts with Allylsilanes under Merged Gold/Visible-Light Photoredox Catalysis

A method for the cross-coupling reactions of aryldiazonium salts with trialkylallylsilanes via merged gold/photoredox catalysis is described. The reaction is proposed to proceed through a photoredox-promoted generation of an electrophilic arylgold(III) intermediate that undergoes transmetalation with allyltrimethylsilane to form allylarenes.