77334-06-6 Usage
Uses
Used in Pharmaceutical Industry:
[8]-Gingerdione is used as an anti-inflammatory agent for its ability to inhibit the production of nitric oxide, which is associated with inflammation.
[8]-Gingerdione is used as an antioxidant for its capacity to scavenge free radicals, protecting cells from oxidative stress.
Used in Anticancer Applications:
[8]-Gingerdione is used as a potential cancer therapeutic agent for its ability to induce apoptosis in cancer cells, making it a candidate for cancer treatment.
Used in Nutraceutical Industry:
[8]-Gingerdione is used as a natural health supplement for its various health benefits and therapeutic potential, contributing to overall well-being and supporting the body's defense mechanisms against diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 77334-06-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,3,3 and 4 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 77334-06:
(7*7)+(6*7)+(5*3)+(4*3)+(3*4)+(2*0)+(1*6)=136
136 % 10 = 6
So 77334-06-6 is a valid CAS Registry Number.
77334-06-6Relevant academic research and scientific papers
Syntheses of the (+/-)--Gingerols (Pungent Principles of Ginger) and Related Compounds through Regioselective Aldol Condensations: Relative Pungency Assays
Dennif, Phillip,Macleod, Ian,Whiting, Donald A.
, p. 82 - 87 (2007/10/02)
The deprotonation of trimethylsilylzingerone (13) by lithium di-isopropylamide at -78 deg C has been found to be regioselective (92 : 8 in favour of less-substituted enolate): the anion was condensed with alkanals and acyl imidazoles to give convenient syntheses of (+/-)--- and --gingerols (1) and -, -, and -gingerdiones (9).Similary, 3-methoxy-4-trimethylsilyloxybenzylideneacetone (17) gave the (+/-)---dehydrogingerols (8) and -, -, and -dehydrogingerdiones (10).The aldol reaction to -gingerol and methyl -gingerol was also conducted through a vinyloxyborane or through the enol silyl ether (TiCl4 catalysis).Results of organoleptic assays on these compounds are discussed, and the relation between pungency in the gingerols and in capsaicin is commented on.The aldol method was also used to synthesise the natural β-ketols(+/-)-daphneolone (25) and (+/-)-hexahydrocurcumin (4).
