7734-80-7

Usage

Uses

Used in Pharmaceutical Industry:
Coumarin-6-carboxylic acid is used as a synthetic intermediate for the development of various pharmaceutical products. Its unique properties make it a valuable component in the synthesis of drugs with potential therapeutic applications.
Used in Biological and Biochemical Research:
Coumarin-6-carboxylic acid is used as a specific stain and tracer in biological and biochemical research. Its good fluorescence properties enable researchers to track and analyze particle translocation behaviors in cells, providing valuable insights into cytochemistry and drug delivery mechanisms.
Used in Drug Delivery Systems:
Coumarin-6-carboxylic acid is used in the development of drug delivery systems to improve the efficiency and effectiveness of drug administration. Its properties allow for the design of targeted drug delivery systems that can enhance the therapeutic outcomes of various treatments.
Used in Analytical Techniques:
Coumarin-6-carboxylic acid is used in various analytical techniques to study the behavior of molecules within cells. Its fluorescence properties make it an ideal tracer for tracking and analyzing the movement and interaction of particles within cellular environments, contributing to a better understanding of cellular processes and mechanisms.

InChI:InChI=1/C10H6O4/c11-9-4-2-6-5-7(10(12)13)1-3-8(6)14-9/h1-5H,(H,12,13)

Upstream product

• 50396-61-7 2-oxo-2H-chromene-6-carbonitrile 
• 617-48-1 malic acid 
• 99-96-7 4-hydroxy-benzoic acid 
• 1310535-74-0 6-vinyl-2H-chromen-2-one 
• 51690-26-7 coumarin-6-carboxaldehyde 
• 92-48-8 6-methylcoumarin 

Downstream Products

• 947408-90-4 6-(2,4-dimethoxybenzoyl)chromen-2-one 
• 874204-71-4 methyl 3-[2-isobutoxy-5-(4-isobutoxybenzoyl)phenyl]propionate 
• 874204-75-8 methyl 3-[2-hydroxy-5-(4-isobutoxybenzoyl)phenyl]propionate 
• 269082-09-9 3-(2-isobutoxy-5-(4-isobutoxybenzoyl)phenyl)propionic acid 
• 947408-91-5 6-(2,4-dihydroxybenzoyl)chromen-2-one 
• 947408-93-7 6-(2-hydroxy-4-cyclopentyloxybenzoyl)coumarin 
• 530141-60-7 methyl 3-[2-hydroxy-5-(2-hydroxy-4-cyclopentyloxybenzoyl)phenyl]propionate 
• 947409-01-0 methyl 3-[2-[(2-trityl-3-keto-benzisoxazol-6-yl)methoxy]-5-(2-hydroxy-4-cyclopentyloxybenzoyl)phenyl]propionate 

Relevant academic research and scientific papers

A 4,4 '-di-substituted diphenyl ketone compound and its preparation method

The invention provides a 4,4'-dibasic benzophenone compound which has a structure shown in the following formula I. The compound can well inhibit activities of an AP-1 protein and an NDM-1 protein and has the IC50 value of 52.93 plus and minus 11.86muM fo

FUSED 1,4-DIHYDRODIOXIN DERIVATIVES AS INHIBITORS OF HEAT SHOCK TRANSCRIPTION FACTOR 1

The present invention relates to compounds of formula I wherein A1, A2 R4 and Q are as defined herein. The compounds of the present invention are inhibitors of heat shock factor 1 (HSF1). In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.

Oxidative cleavage of olefins by in situ-generated catalytic 3,4,5,6-tetramethyl-2-iodoxybenzoic acid/oxone

Oxidative cleavage of a variety of olefins to the corresponding ketones/carboxylic acids is shown to occur in a facile manner with 3,4,5,6-tetramethyl-2-iodobenzoic acid (TetMe-IA)/oxone. The simple methodology involves mere stirring of the olefin and catalytic amount (10 mol %) of TetMe-IA and oxone in acetonitrile-water mixture (1:1, v/v) at rt. The reaction mechanism involves initial dihydroxylation of the olefin with oxone, oxidative cleavage by the in situ-generated 3,4,5,6-tetramethyl-2-iodoxybenzoic acid (TetMe-IBX), and oxidation of the aldehyde functionality to the corresponding acid with oxone. Differences in the reactivities of electron-rich and electron-poor double bonds have been exploited to demonstrate chemoselective oxidative cleavage in substrates containing two double bonds.

COSMETIC OR DERMATOLOGICAL COMPOSITION COMPRISING A POLYMER BEARING JUNCTION GROUPS, AND COSMETIC TREATMENT PROCESS

The present patent application relates to a cosmetic or dermatological composition comprising, in a cosmetically or dermatologically acceptable medium, a polymer comprising: (a) a polymer backbone that may be obtained by reaction: of a polyol comprising 3 to 6 hydroxyl groups;of a monocarboxylic acid containing 6 to 32 carbon atoms;of a polycarboxylic acid comprising at least two carboxylic groups COOH, and/or of a cyclic anhydride such as a polycarboxylic acid and/or of a lactone comprising at least one carboxylic group COOH; and(b) at least one junction group linked to the said polymer backbone and capable of establishing H bonds with one or more partner junction groups, each pairing of a junction group involving at least three H (hydrogen) bonds. The patent application also concerns a cosmetic treatment process using the said composition.

PROCESS FOR PRODUCTION OF 3-[5-[4-(CYCLOPENTYLOXY)-2-HYDROXYBENZOYL]-2-[(3-HYDROXY-1,2-BEZISOXAZOL-6-YL)METHOXY]PHENYL]PROPIONATE ESTER AND INTERMEDIATE FOR THE PROCESS

A preparation method using as an intermediate 6-(halomethyl)-1,2-benzisoxazol-3(2H)-one derivative represented by general formula wherein R5 is a methyl group that is substituted with one or more optionally substituted phenyl groups, or an opti