77345-53-0

Upstream product

• 186581-53-3 diazomethane 
• 13504-86-4 (2S,4S)-1-benzyloxycarbonyl-4-hydroxyproline 
• 13504-85-3 (2S,4R)-1-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid 
• 51-35-4 4R-4-hydroxyproline 
• 501-53-1 benzyl chloroformate 
• 64187-48-0 methyl (2S,4R)-1-benzyloxycarbonyl-4-hydroxypyrrolidine-2-carboxylate 
• 80-48-8 methyl p-toluene sulfonate 

Downstream Products

• 102013-10-5 cis-1-benzyloxycarbonyl-4-(toluene-4-sulfonyloxy)-L-proline 
• 113949-40-9 N-(benzyloxycarbonyl)-trans-4-(methylthio)-L-proline 
• 83552-11-8 N-(benzyloxycarbonyl)-trans-4-(phenylthio)-L-proline 
• 83552-14-1 trans-4-(phenylthio)-L-proline methyl ester monohydrochloride 
• 83552-30-1 (trans)-1-[N-[(S)-1Carboxy-3-phenylpropyl]-L-alanyl]-4-(methylthio)-L-proline 
• 83552-13-0 trans-4-(phenylthio)-L-propline 
• 83602-04-4 [1(S),4R]-1-[N-(1-carboxy-3-phenylpropyl)-L-alanyl]-4-(phenylthio)-L-proline 
• 83624-61-7 trans-4-methylsulfanyl-L-proline 
• 473806-21-2 4-tertbutyloxycarbonylamino-L-trans-proline methyl ester 
• 189215-90-5 1-benzyl 2-methyl (2S,4R)-4-(tert-butoxycarbonylamino)pyrrolidine-1,2-dicarboxylate 
• 787615-53-6 N-1-(benzyloxycarbonyl)-(4R)-(tert-butyloxycarbonylamino)-(2S)-(thymin-1-ylmethyl)pyrrolidine 
• 787615-51-4 N-1-(benzyloxycarbonyl)-(4R)-(tert-butyloxycarbonylamino)-(2S)-(O-mesylmethyl)pyrrolidine 
• 787615-49-0 (2S,4R)-N-1-(benzyloxycarbonyl)-4-(tert-butyloxycarbonylamino)pyrrolidin-2-methanol 
• 189215-89-2 (2S,4R)-N-1-(benzyloxycarbonyl)-4-azidoproline methyl ester 

Relevant academic research and scientific papers

Chimeric (aeg-pyrrolidine)PNAs: Synthesis and stereo-discriminative duplex binding with DNA/RNA

The design and facile conversion of naturally occurring 4-hydroxyproline to all four diastereomers of thymine pyrrolidine PNA monomer, (2R,4S)-adenine, -guanine and -cytosine monomers and their incorporation into duplex forming PNA oligomers is reported,

Two prolines with a difference: contrasting stereoelectronic effects of 4R/S-aminoproline on triplex stability in collagen peptides [pro(X)-pro(Y)-Gly]n.

4R/S-Aminoprolines when present in the X-position of collagen peptide [pro(X)-pro(Y)-Gly]n exhibit pH- and stereochemistry-dependent effects on triplex stability.