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Z-Cys(BzlOMe)-ONSu, also known as N-benzyloxycarbonyl-S-(4-methoxybenzyl)-L-cysteine N-succinimidyl ester, is a chemical compound derived from the amino acid cysteine. It features a benzyloxycarbonyl (Z) protecting group on the amino group, a 4-methoxybenzyl (BzlOMe) protecting group on the thiol group, and a succinimidyl ester (ONSu) reactive group. Z-Cys(BzlOMe)-ONSu is commonly used in peptide synthesis and protein modification, as the protecting groups can be selectively removed under mild conditions, allowing for controlled coupling reactions. The succinimidyl ester group is particularly reactive towards primary amines, making it a useful tool for conjugating peptides or proteins to other molecules, such as antibodies or fluorescent tags, in biological research and drug development.

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  • 77374-43-7 Structure
  • Basic information

    1. Product Name: Z-Cys(BzlOMe)-ONSu
    2. Synonyms: Z-Cys(BzlOMe)-ONSu
    3. CAS NO:77374-43-7
    4. Molecular Formula:
    5. Molecular Weight: 472.519
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 77374-43-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Z-Cys(BzlOMe)-ONSu(CAS DataBase Reference)
    10. NIST Chemistry Reference: Z-Cys(BzlOMe)-ONSu(77374-43-7)
    11. EPA Substance Registry System: Z-Cys(BzlOMe)-ONSu(77374-43-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 77374-43-7(Hazardous Substances Data)

77374-43-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 77374-43-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,3,7 and 4 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 77374-43:
(7*7)+(6*7)+(5*3)+(4*7)+(3*4)+(2*4)+(1*3)=157
157 % 10 = 7
So 77374-43-7 is a valid CAS Registry Number.

77374-43-7Relevant articles and documents

Studies Relating to the Ferredoxins. Part 3. The Synthesis of Some Cysteine-Glycine Peptides for Iron-Sulphur Complexing Studies

Balasubramaniam, Ambikaipakan,Burt, Roger J.,Christou, George,Ridge, Brian,Rydon, H. N.

, p. 310 - 317 (2007/10/02)

Three peptides with the general structure Ac-Gly2.(Cys.Glym)n.Cys.Gly3.Cys.Gly2.NH2 (1; m = 2 or 3; n = 0 or 1), four with the general structure Ac.Gly2.Cysn.Gly2.NH2

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