77375-77-0Relevant academic research and scientific papers
NITROGEN-CONTAINING HETEROCYCLYL KETONES AND METHODS OF USE
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Page/Page column 133, (2008/12/08)
Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.
Pyridazinones. 2. Synthesis and Antisecretory and Antiulcer Activities of Thiourea and 2-Cyanoguanidine Derivatives
Yamada, Toshihiro,Nobuhara, Youichi,Shimamura, Hiroshi,Tsukamoto, Yoshitsugu,Yoshihara, Kazuo,et al.
, p. 373 - 381 (2007/10/02)
In an effort to develop new types of antiulcer agents, we synthesized a series of novel 2-- and 2--3-(2H)-pyridazinone derivatives.All target compounds were evaluated for gastric antisecretory activity in the
Pyridazinones. IV. Synthesis, antisecretory and antiulcer activities of urea derivatives
Yamada,Tsukamoto,Shimamura,et al.
, p. 209 - 214 (2007/10/02)
The synthesis of a series of 6-phenyl-3(2H)-pyridazinone derivatives having urea moiety via the addition of free amines into various isocyanates or carbamoyl chlorides was described. The gastric antisecretory activity of these compounds was evaluated usin
