83675-81-4

Upstream product

• 2166-31-6 6-phenylpyridazin-3(2H)-one 
• 574-98-1 2-(2-bromoethyl)isoindoline-1,3-dione 
• 136918-14-4 phthalimide 
• 23916-77-0 2-(2-hydroxyethyl)-6-phenyl-3(2H)-pyridazinone 

Downstream Products

• 77375-77-0 2-(2-aminoethyl)-6-phenylpyridazin-3(2H)-one 
• 87666-25-9 1-Methyl-3-[2-(6-oxo-3-phenyl-6H-pyridazin-1-yl)-ethyl]-urea 
• 87666-24-8 [2-(6-Oxo-3-phenyl-6H-pyridazin-1-yl)-ethyl]-urea 
• 77375-72-5 1-Cyclohexyl-3-[2-(6-oxo-3-phenyl-6H-pyridazin-1-yl)-ethyl]-thiourea 
• 77375-73-6 1-[2-(6-Oxo-3-phenyl-6H-pyridazin-1-yl)-ethyl]-3-phenyl-thiourea 
• 85397-00-8 C₁₆H₁₈N₆O 
• 79461-13-5 C₁₅H₁₆N₆O 
• 79460-70-1 2-<2-(3-cyano-2-methyl-1-isothioureido)ethyl>-6-phenyl-3(2H)-pyridazinone 
• 85396-99-2 C₁₄H₁₄N₆O 
• 85396-72-1 1-Ethyl-3-[2-(6-oxo-3-phenyl-6H-pyridazin-1-yl)-ethyl]-thiourea 
• 77375-71-4 2-<2-(3-methylthioureido)ethyl>-6-phenyl-3(2H)-pyridazinone 

Relevant academic research and scientific papers

NITROGEN-CONTAINING HETEROCYCLYL KETONES AND METHODS OF USE

Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Pyridazinones. 2. Synthesis and Antisecretory and Antiulcer Activities of Thiourea and 2-Cyanoguanidine Derivatives

In an effort to develop new types of antiulcer agents, we synthesized a series of novel 2-- and 2--3-(2H)-pyridazinone derivatives.All target compounds were evaluated for gastric antisecretory activity in the

Pyridazinones. IV. Synthesis, antisecretory and antiulcer activities of urea derivatives

The synthesis of a series of 6-phenyl-3(2H)-pyridazinone derivatives having urea moiety via the addition of free amines into various isocyanates or carbamoyl chlorides was described. The gastric antisecretory activity of these compounds was evaluated usin