7738-99-0

Usage

Uses

Used in Pharmaceutical Drug Synthesis:
2-(4-chlorophenyl)thiazolidine is used as a key intermediate in the synthesis of various pharmaceutical drugs. Its unique structure and reactivity allow for the development of new drug candidates with potential therapeutic applications.
Used in Organic Chemistry Research:
In the field of organic chemistry, 2-(4-chlorophenyl)thiazolidine serves as a valuable tool for researchers and chemists. Its versatile reactivity enables the exploration of novel chemical reactions and the synthesis of complex organic compounds, contributing to the advancement of organic chemistry.
Used in Material Science:
2-(4-chlorophenyl)thiazolidine can also be employed in material science for the development of new materials with specific properties. Its unique structure and reactivity can be utilized to create materials with applications in various industries, such as electronics, coatings, and polymers.

InChI:InChI=1/C9H10ClNS/c10-8-3-1-7(2-4-8)9-11-5-6-12-9/h1-4,9,11H,5-6H2

Upstream product

• 156-57-0 2-mercaptoethylamine hydrochloride 
• 104-88-1 4-chlorobenzaldehyde 
• 60-23-1 Cysteamine 

Downstream Products

• 67189-33-7 2-(4-chloro-phenyl)-2,3-dimethyl-thiazolidine 
• 67224-60-6 2-(4-chloro-phenyl)-3-methyl-thiazolidine 
• 112561-97-4 2-(4-Chloro-phenyl)-thiazolidine-3-carbothioic acid methylamide 

Relevant academic research and scientific papers

Substituted tetrahydropyrrolo[2,1-b]oxazol-5(6H)-ones and tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones as hypoglycemic agents

A series of substituted tetrahydropyrrolo[2,1-b]oxazol-5(6H)-ones and tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones was synthesized from amino alcohols or amino thiols and keto acids. A pharmacological model based on the results obtained with these compounds led to the synthesis and evaluation of a series of isoxazoles and other monocyclic compounds. These were evaluated for their ability to enhance glucose utilization in cultured L6 myocytes. The in vivo hypoglycemic efficacy and potency of these compounds were evaluated in a model of type 2 diabetes mellitus (non-insulin-dependent diabetes mellitus), the ob/ob mouse. 25a(2S) (SDZ PGU 693) was selected for further pharmacological studies.

Comparative radioprotective activity of various pentagonal compounds with two heteroatomes

Various heterocyclic compounds with two heteroatomes were synthesized and their potential radioprotective activity was tested. This study shows the interest of phenylthiazolidines derivatives in chemical radioprotection.