77385-75-2Relevant academic research and scientific papers
Cyclic Diaryl λ3-Bromanes: A Rapid Access to Molecular Complexity via Cycloaddition Reactions
Lanzi, Matteo,Ali Abdine, Racha Abed,De Abreu, Maxime,Wencel-Delord, Joanna
supporting information, p. 9047 - 9052 (2021/12/06)
Biaryls have widespread applications in organic synthesis. However, sequentially polysubstituted biaryls are underdeveloped due to their challenging preparation. Herein, we report the synthesis of dissymetric 2,3,2′,3′,4-substituted biaryls via pericyclic reactions of cyclic diaryl λ3-bromanes. The functional groups tolerance and atom economy allow access to molecular complexity in a single reaction step. Continuous flow protocol has been designed for the scale-up of the reaction, while postfunctionalizations have been developed taking advantage of the residual Br-atom.
Dissociative ionization of aryl-substituted vinyl bromides in the gas phase: Experimental and computational evidence for the formation of stable α-arylvinyl cations both by direct means and spontaneous exothermic isomerization of unstable isomeric ions
Apeloig, Yitzhak,Franke, Wilfried,Rappoport, Zvi,Schwarz, Helmut,Stahl, Daniel
, p. 2770 - 2780 (2007/10/02)
The kinetic energy release T which accompanies the Br· loss from ionized (E)- and (Z)-β-bromostyrenes (5 and 6) in the gas phase is higher by 0.7 ± 0.03 kcal mol-1 than that from the molecular ion of α-bromostyrene (4). Together with both colli
