773873-68-0

Usage

Uses

Used in Pharmaceutical Industry:
METHYL 2,3,4-TRIFLUOROBENZOATE is used as an active pharmaceutical ingredient for the development of various medications. Its unique chemical properties contribute to the efficacy and potency of the drugs produced.
Used in Pesticide Industry:
METHYL 2,3,4-TRIFLUOROBENZOATE is used as an insecticide and herbicide in the formulation of pest control products. Its insecticidal and herbicidal properties make it a valuable component in the creation of effective solutions for agricultural and horticultural applications.
Used in Organic Synthesis:
METHYL 2,3,4-TRIFLUOROBENZOATE is used as a reagent in organic synthesis, facilitating the production of a wide range of organic compounds. Its versatility in chemical reactions allows for the synthesis of various target molecules.
Used as a Solvent in Chemical Reactions:
METHYL 2,3,4-TRIFLUOROBENZOATE is utilized as a solvent in various chemical processes. Its ability to dissolve a broad spectrum of substances makes it a valuable component in numerous chemical reactions.
Safety Precautions:
It is important to handle METHYL 2,3,4-TRIFLUOROBENZOATE with care, as it may cause irritation to the skin, eyes, and respiratory system upon exposure. Proper safety measures should be taken to minimize the risk of adverse effects.

Upstream product

• 67-56-1 methanol 
• 61079-72-9 2,3,4,-trifluorobenzoic acid 

Downstream Products

• 1073129-44-8 methyl 3,4-difluoro-2-methylaminobenzoate 
• 1073129-45-9 methyl 2-(3-ethoxy-N-methyl-3-oxopropanamido)-3,4-difluorobenzoate 
• 247034-24-8 tert-butyl (2S)-benzenesulfonylamino-3-[2,3-difluoro-4-{4-(pyrimidin-2-ylamino)piperidin-1-yl}benzoylamino]propionate 
• 247035-31-0 2,3-difluoro-4-{4-(pyrimidin-2-ylamino)piperidin-1-yl}benzoic acid 
• 247035-30-9 methyl 2,3-difluoro-4-{4-(pyrimidin-2-ylamino)piperidin-1-yl}benzoate 
• 247035-27-4 Methyl 2,3-difluoro-4-{4(methanesulfonyloxy)piperidin-1-yl}benzoate 
• 247035-28-5 4-(4-azido-piperidin-1-yl)-2,3-difluoro-benzoic acid methyl ester 
• 247035-29-6 methyl (4-aminopiperidin-1-yl)-2,3-difluorobenzoate 
• 1012867-26-3 4-Dimethylamino-2.3-difluoro-benzoic acid methyl ester 
• 879009-99-1 methyl 4-{(3S)-aminopiperidin-1-yl}-2,3-difluorobenzoate 

Relevant academic research and scientific papers

Synthesis and biological evaluation of indazole derivatives

The inhibition of neuronal and inducible nitric oxide synthases (nNOS and iNOS) by a series of 36 indazoles has been evaluated, showing that most of the assayed derivatives are better iNOS than nNOS inhibitors. A parabolic model relating the iNOS inhibiti

Aminopiperidine derivates as integrin αvβ3 antagonists

An objective of the present invention is to provide compounds having integrin αvβ3antagonistic activity, cell adhesion inhibitory activity, GP IIb/IIIa antagonistic activity, and/or human platelet aggregation inhibitory activity, and, therapeutic agents for treating cardiovascular diseases, angiogenesis-related diseases, cerebrovascular diseases and the like and for inhibiting platelet aggregation. The derivatives according to the present invention are compounds represented by formula (I) or pharmaceutically acceptable salts or solvates thereof: wherein A represents a five- to seven-membered heterocyclic group containing two nitrogen atoms or the like; D represents >NH2, >CH2or the like; X and Z represent CH or a nitrogen atom; R7and R8represent alkyl, halogen or the like; Q represents >C═O, >CH2or the like; R9represents H, alkyl, aralkyl or the like; R10represents H, alkynyl or the like; R11represents H, substituted amino or the like; R12represents H or alkyl; m is 0 to 5; n is 0 to 4; p and q are each 1 to 3; and r is 0 or 1.

Methods of treatment with compounds having RARα receptor specific or selective activity

Retinoid compounds which act specifically or selectively on RARα receptor subtypes in preference over RARβ and RARγ receptor subtypes, posses desirable pharmaceutical properties associated with retinoids, and are particularly suitable for treatment of tumors, such as acute monocytic leukemia, cervical carcinoma, myeloma, ovarian carcinomas and head and neck carcinomas, without having one or more undesirable side effects of retinoids, such as inducement of weight loss, mucocutaneous toxicity, skin irritation and teratogenecity.

Substituted heteroarylamides having retinoid-like biological activity

Compounds of the formula STR1 wherein the symbols have the meaning described in the specification, have retinoid-like biological activity.

Aryl or heteroaryl amides of tetrahydronaphthalene, chroman, thiochroman and 1,2,3,4,-tetrahydroquinoline carboxylic acids, having an electron withdrawing substituent in the aromatic or heteroaromatic moiety, having retinoid-like biological activity

Compounds of the formula STR1 where the symbols have the meaning defined in the specification have retinoid-like biological activity.