774-10-7Relevant academic research and scientific papers
Synergistic steric effects in the development of a palladium-catalyzed alkyne carbohalogenation: Stereodivergent synthesis of vinyl halides
Le, Christine M.,Menzies, Perry J. C.,Petrone, David A.,Lautens, Mark
, p. 254 - 257 (2015/02/19)
We report our finding that by exploiting the synergistic steric effects between substrate and catalyst, an intramolecular Pd-catalyzed alkyne carbohalogenation can be achieved. This operationally simple method uses the bulky Pd/ Q-Phos combination and all
Regioselective hydrostannation of highly hindered arylalkynes under ortho-directing effects
Hamze, Abdallah,Le Menez, Patrick,Provot, Olivier,Morvan, Estelle,Brion, Jean-Daniel,Alami, Mouad
experimental part, p. 8698 - 8706 (2010/11/18)
Palladium-catalyzed hydrostannation reactions of ortho-disubstituted arylalkynes were achieved with total stereo- and regio-selectivity in THF at room temperature. The regioselectivity was found to be under the control of the ortho-substituents (ortho-dir
Synthesis of benzo[g]isochromenes through Photo-Dehydro-Diels-Alder reaction
Wessig, Pablo,Mueller, Gunnar,Herre, Robert,Kuehn, Andreas
, p. 2694 - 2719 (2007/10/03)
The Photo-Dehydro-Diels-Alder (PDDA) reaction is shown to be a versatile method for the preparation of highly functionalized naphthalenes. Thus, ketones 1 could be cyclized to the 1H-benzo[g]isochromen-4-(3H)-ones 11 and 12, mostly in good yields. The influence of various substituents on the regioselectivity of the reaction was investigated, and the mechanism is discussed based on theoretical calculations.
