7740-04-7

Upstream product

• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 704912-40-3 7-methoxyquinolino[2',3':3,4]pyrrolo[2,1-b]quinazolin-11(13H)-one 
• 93945-52-9 2-p-Toluolsulfonyloxy-3-methoxy-benzoesaeure 
• 138474-96-1 3-(2-hydroxy-3-methoxyphenyl)-1-pentylpropen-1-one 
• 20041-61-6 2-hydroxy-3-methoxy-4-nitrobenzaldehyde 
• 2426-86-0 2-hydroxy-3-methoxy-6-nitrobenzaldehyde 
• 1026513-31-4 3-methoxy-6-nitro-2-(p-tolylsulfonyl)benzaldehyde 
• 1027549-38-7 Toluene-4-sulfonic acid 6-formyl-2-methoxy-3-nitro-phenyl ester 
• 78515-26-1 C₃₀H₂₈O₈S₂ 
• 138475-01-1 Toluene-4-sulfonic acid 2-methoxy-6-((E)-3-oxo-oct-1-enyl)-phenyl ester 

Relevant academic research and scientific papers

Concise approach to mono- And disubstituted luotonin A analogs and their cytotoxicity test

A concise approach for the preparation of luotonin A analogs has been developed. The new synthetic route contains an anion-assisted intramolecular double hetero Diels Alder reaction and a direct oxidative cross coupling reaction. Some synthetic luotonin A analogs show cytotoxic activities against Daudi and Jurkat human cancer cells as potent as camptothecin.

A photocleavable auxiliary for extended native chemical ligation

To extend the scope of native chemical ligations beyond X-Cys connections, auxiliaries that contain thiol moieties were developed to mimic the function of the Cys residue in the ligation reaction/capture step. Auxiliaries known so far feature complicated

A concise approach to the preparation of 2-hydroxydiarylketones by an intramolecular acyl radical ipso substitution

Substituted 2-hydroxydiarylketones have been simply prepared using an intramolecular acyl radical [1,6] ipso substitution reaction. (C) 2000 Elsevier Science Ltd.

Dihydroxynitrobenzaldehydes and Hydroxymethoxynitrobenzaldehydes: Synthesis and Biological Activity as Catechol-O-methyltransferase Inhibitors

A series of nitro derivatives of dihydroxy- and hydroxymethoxybenzaldehyde was synthesized and tested as potential inhibitors of partially purified pig liver catechol-O-methyltransferase (COMT).All the dihydroxynitrobenzaldehydes prepared were potent inhibitors of COMT, but only one hydroxymethoxynitrobenzaldehyde (3-hydroxy-4-methoxy-5-nitrobenzaldehyde) showed activity as a COMT inhibitor.Although previously reported data showed that the presence of electron-withdrawing substituents at position 5 seemed to be very important for activity as COMT inhibitor, our results suggest that the requirement necessary to enhance the activity of the dihydroxynitrobenzaldehyde derivatives toward COMT is the presence of the nitro group in a position ortho with respect to one hydroxyl group.The assayed compounds showed a reversible inhibition of COMT, which was mixed for all the dihydroxynitro derivatives but noncompetitive for 3-hydroxy-4-methoxy-5-nitrobenzaldehyde when pyrocatechol was the variable substrate and uncompetitive in all the inhibitors with respect to S-adenosyl-L-methionine.

Anthelmintic activity of some 3-substituted phenyl-1-alkyl or phenyl propenones and propenamides

In a search for new anthelmintic compounds, α,β-unsaturated ketones and amides were synthetized. Their anthelmintic activity was tested against two gastrointestinal worms, a nematode Syphacia obvelata and a cestode Hymenolepis nana. Structure-activity rel