77400-46-5 Usage
Nitrosooxazolidine derivative
A class of compounds 2,2,5-trimethyl-3-nitroso-1,3-oxazolidine belongs to a specific group of chemical substances, which are derivatives of nitrosooxazolidine.
Pharmaceutical intermediates
Commonly used in the synthesis of pharmaceuticals These compounds serve as starting materials or building blocks in the creation of various drugs and medications.
Agrochemicals
Used in the synthesis of 2,2,5-trimethyl-3-nitroso-1,3-oxazolidine is also utilized in the production of chemicals for agricultural purposes, such as pesticides and fertilizers.
Unique structure and properties
Valuable in organic synthesis and medicinal chemistry The specific arrangement of atoms and the properties of 2,2,5-trimethyl-3-nitroso-1,3-oxazolidine make it a useful and important substance in the fields of organic synthesis and the development of new medicines.
Potentially hazardous and carcinogenic
Handle with caution Nitroso compounds, including this specific compound, are known to pose potential health risks and may cause cancer. It is essential to follow proper safety procedures when working with this substance.
Check Digit Verification of cas no
The CAS Registry Mumber 77400-46-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,7,4,0 and 0 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 77400-46:
(7*7)+(6*7)+(5*4)+(4*0)+(3*0)+(2*4)+(1*6)=125
125 % 10 = 5
So 77400-46-5 is a valid CAS Registry Number.
77400-46-5Relevant academic research and scientific papers
Deamination of Primary Aminoalkanols. Formation of Substituted N-Nitroso-1,3-oxazolidines and N-Nitroso-1,3-tetrahydrooxazines
Saavedra, Joseph E.
, p. 2610 - 2614 (2007/10/02)
The deamination of 2-amino- and 3-aminoalkanols in the presence of nitrous acid is reported.The 2-aminoalkanols generated aldehydes upon loss of nitrogen, followed by oxazolidine formation by reaction with starting material and finally nitrosation to substituted N-nitroso-1,3-oxazolidines.Ethanolamine gave N-nitroso-2-methyl-1,3-oxazolidine; 2-amino-2-methyl-1-propanol was converted to N-nitroso-2-isopropyl-4,4-dimethyl-1,3-oxazolidine.Deamination of 1-amino-2-propanol gave propionaldehyde, which upon further reaction produced cis- and trans-N-nitroso-2-ethyl-5-methyl-1,3-oxazolidines. (E)- and (Z)-N-nitroso-2-ethyl-4-methyl-1,3-oxazolidines were obtained from the deamination of 2-amino-1-propanol.Propionaldehyde and formaldehyde were produced by diazotiazation of 1-amino-3-propanol.Further reaction of the aldehydes with unreacted amine formed N-nitroso-1,3-tetrahydrooxazine and N-nitroso-2-ethyl-1,3-tetrahydrooxazine.Nuclear magnetic resonance and deuterium-exchange studies of these compounds are discussed.
