77401-25-3

Basic information

• Product Name: 1,6-dimethyl-4-(propan-2-yl)naphthalene-2,7-diol
• Synonyms: 2,7-Naphthalenediol, 1,6-dimethyl-4-(1-methylethyl)-
• CAS NO: 77401-25-3
• Molecular Formula: C₁₅H₁₈O₂
• Molecular Weight: 230.3022
• Mol File: 77401-25-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 409°C at 760 mmHg
• Flash Point: 196°C
• Density: 1.134g/cm³
• Vapor Pressure: 2.84E-07mmHg at 25°C
• Refractive Index: 1.624
• CAS DataBase Reference: 1,6-dimethyl-4-(propan-2-yl)naphthalene-2,7-diol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-dimethyl-4-(propan-2-yl)naphthalene-2,7-diol(77401-25-3)
• EPA Substance Registry System: 1,6-dimethyl-4-(propan-2-yl)naphthalene-2,7-diol(77401-25-3)

Safety Data

• Hazardous Substances Data: 77401-25-3(Hazardous Substances Data)

Upstream product

• 68233-94-3 4‐isopropyl‐7‐methoxy‐1,6‐dimethylnaphthalen‐2‐ol 
• 80713-20-8 methyl β-(3-methyl-4-methoxybenzoyl)propionate 
• 77996-10-2 4-Hydroxy-4-(4-methoxy-3-methylphenyl)-5-methyl-hexanoic Acid Lactone 
• 77996-11-3 4-Isopropyl-7-methoxy-1,6-dimethyl-1,2,3,4-tetrahydro-naphthalen-1-ol 
• 2954-68-9 4-(4-methoxy-3-methylphenyl)-4-oxo-butyric acid ethyl ester 
• 80736-45-4 1,2,3,4-Tetrahydro-4-isopropyl-7-methoxy-6-methyl-1-naphthalenone 
• 70143-26-9 1,2,3,4-tetrahydro-1,2-dihydroxy-4-isopropyl-7-methoxy-1,6-dimethylnaphthalene 
• 70143-25-8 7-Methoxy-α-calacorene 
• 70143-24-7 4-(4-methoxy-3-methylphenyl)-5-methylhexanoic acid 
• 68233-93-2 1,2,3,4-Tetrahydro-4-isopropyl-7-methoxy-1,6-dimethyl-2-naphthalenone 

Relevant articles and documents

Gossypium Cadinanes and Their Analogues: Synthesis of Lacinilene C, 2,7-Dihydroxycadalene, and Their Methyl Ethers

The total synthesis of lacinilene C methyl ether has been accomplished in ten steps with an overall, optimal yield of 38percent by starting with o-methylanisole.Formation of the key α-aryl-α-ketol functionality, which is particularly sensitive to oxidation, was accomplished by stepwise oxidation reactions based on the use of N-methylmorpholine N-oxide/osmium tetraoxide acting on alkene and trimethylsilyl enol ether functionality.Other oxidations could be accomplished by using dichlorodicyanobenzoquinone to generate unsaturation adjacent to the α-ketol group or to form substituted naphtalenes.These reactions permitted adjustment of the oxidation level and oxygenation pattern of the key intermediate, 7-methoxy-α-calacorene (3,4-dihydro-4-isopropyl-7-methoxy-1,6-dimethylnaphthalene), to accomplish the synthesis of 2-hydroxy-7-methoxycadalene, 2,7-dihydroxycadalene, 7-methoxycadalene, and 7-hydroxycadalene, in addition to lacinilene C and its methyl ether.