70143-24-7

Basic information

• Product Name: Benzenebutanoic acid, 4-Methoxy-3-Methyl-g- (1-Methylethyl)
• Synonyms: Benzenebutanoic acid, 4-Methoxy-3-Methyl-g- (1-Methylethyl)
• CAS NO: 70143-24-7
• Molecular Formula: C₁₅H₂₂O₃
• Molecular Weight: 250.33338
• Mol File: 70143-24-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenebutanoic acid, 4-Methoxy-3-Methyl-g- (1-Methylethyl)(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenebutanoic acid, 4-Methoxy-3-Methyl-g- (1-Methylethyl)(70143-24-7)
• EPA Substance Registry System: Benzenebutanoic acid, 4-Methoxy-3-Methyl-g- (1-Methylethyl)(70143-24-7)

Safety Data

• Hazardous Substances Data: 70143-24-7(Hazardous Substances Data)

Upstream product

• 33446-14-9 4-(4-methoxy-3-methylphenyl)-4-oxobutyric acid 
• 578-58-5 2-methylmethoxybenzene 
• 77996-10-2 4-Hydroxy-4-(4-methoxy-3-methylphenyl)-5-methyl-hexanoic Acid Lactone 
• 920-39-8 isopropylmagnesium bromide 
• 80713-20-8 methyl β-(3-methyl-4-methoxybenzoyl)propionate 
• 1068-56-0 isopropylmagnesium iodide 
• 2954-80-5 4-<4-Methoxy-3-methyl-phenyl>-5-methyl-hexansaeure-amid 
• 2954-55-4 3-<4-Methoxy-3-methyl-phenyl>-4-methyl-pent-2-ensaeure-aethylester 
• 2954-57-6 3-<4-Methoxy-3-methyl-phenyl>-4-methyl-pentansaeure 
• 1017122-80-3 3-<4-Methoxy-3-methyl-phenyl>-4-methyl-pentansaeure-chlorid 
• 2954-63-4 1-(4-methoxy-3-methylphenyl)-2-methyl-1-propanone 
• 2954-68-9 4-(4-methoxy-3-methylphenyl)-4-oxo-butyric acid ethyl ester 

Downstream Products

• 77996-13-5 3,4-Dihydro-1-hydroxy-4-isopropyl-7-methoxy-1,6-dimethyl-2(1H)-naphthalenone 
• 77401-25-3 2,7-dihydroxycadalene 
• 68233-94-3 4‐isopropyl‐7‐methoxy‐1,6‐dimethylnaphthalen‐2‐ol 
• 87900-51-4 lacinilene C 
• 56051-00-4 1-hydroxy-4-isopropyl-7-methoxy-1,6-dimethylnaphthalen-2(1H)-one 
• 2102-75-2 7-hydroxycadalene 

Relevant articles and documents

Gossypium Cadinanes and Their Analogues: Synthesis of Lacinilene C, 2,7-Dihydroxycadalene, and Their Methyl Ethers

The total synthesis of lacinilene C methyl ether has been accomplished in ten steps with an overall, optimal yield of 38percent by starting with o-methylanisole.Formation of the key α-aryl-α-ketol functionality, which is particularly sensitive to oxidation, was accomplished by stepwise oxidation reactions based on the use of N-methylmorpholine N-oxide/osmium tetraoxide acting on alkene and trimethylsilyl enol ether functionality.Other oxidations could be accomplished by using dichlorodicyanobenzoquinone to generate unsaturation adjacent to the α-ketol group or to form substituted naphtalenes.These reactions permitted adjustment of the oxidation level and oxygenation pattern of the key intermediate, 7-methoxy-α-calacorene (3,4-dihydro-4-isopropyl-7-methoxy-1,6-dimethylnaphthalene), to accomplish the synthesis of 2-hydroxy-7-methoxycadalene, 2,7-dihydroxycadalene, 7-methoxycadalene, and 7-hydroxycadalene, in addition to lacinilene C and its methyl ether.