77401-28-6Relevant articles and documents
Design, Synthesis, Molecular Docking and Biological Activity of New Piperidine and Piperazine Derivatives of Dichloroacetate as Potential Anticancer Agents
Fereidoonnezhad, Masood,Manouchehrizadeh, Elham,Mostoufi, Azar,Tahanpesar, Elham
, (2020)
Dichloroacetate (DCA) is a small anticancer agent acting through inhibition of pyruvate dehydrogenase kinases (PDKs) and preventing proliferation of tumor growth. In this study, a series of new piperidine and piperazine derivatives of DCA were designed an