77409-16-6Relevant academic research and scientific papers
SYNTHESIS OF 2-AMINO-6-SUBSTITUTED 5,6-DIHYDRO-4H-1,3-THIAZIN-4-ONES FROM α,β-UNSATURATED ACYL ISOTHIOCYANATES
Dzurilla, Milan,Kristian, Pavol,Kutschy, Peter
, p. 2958 - 2964 (2007/10/02)
Reactions of α,β-unsaturated acyl isothiocyanates with primary and secondary amines were studied.Thioureas formed from the weakly basic secondary amines easily underwent cyclization in hot benzene to yield 2,6-disubstituted 5,6-dihydro-4H-1,3-thiazin-4-ones.Their structure was proved by IR, 1H-NMR and mass spectral methods.
