77414-46-1Relevant academic research and scientific papers
A Convenient Approach to 2-Aminobenzo[b]chalcogenophenes Based on Copper-Catalyzed Transformation of 4-(2-Bromophenyl)-1,2,3-chalcogenodiazoles in the Presence of a Base and Amines
Popova,Lyapunova,Petrov,Panikorovskii,Androsov
, p. 689 - 699 (2018/06/14)
The reactions of 4-(2-bromophenyl)-1,2,3-thia-and -selenadiazoles with amines in the presence of potassium carbonate and copper(I) iodide afforded 2-aminobenzo[b]chalcogenophenes. The corresponding thiaand selenamides, prepared by interaction of 4-(2-brom
Cascade Trisulfur Radical Anion (S3?-) Addition/Electron Detosylation Process for the Synthesis of 1,2,3-Thiadiazoles and Isothiazoles
Liu, Bei-Bei,Bai, Hui-Wen,Liu, Huan,Wang, Shun-Yi,Ji, Shun-Jun
, p. 10281 - 10288 (2018/07/25)
Trisulfur radical anion (S3?-) mediated reactions with in situ formed azoalkenes and α,β-usaturated N-sulfonylimines for the construction of 1,2,3-thiadiazoles and isothiazoles has been developed. S3?- is in situ generated from potassium sulfide in DMF. These two approaches provide a new, safe, and simple way to construct 4-subsituted 1,2,3-thiadiazoles, 5-subsituted 1,2,3-thiadiazoles, and isothiazole in good yields. The reactions include the formation of the new C-S and N-S bonds via S3?- addition and electron detosylation under mild conditions.
A convenient synthesis of benzo[b]chalcogenophenes from 4-(2-chloro-5-nitrophenyl)-1,2,3-chalcogenadiazoles
Lyapunova, Anna G.,Androsov, Dmitry A.,Petrov, Mikhail L.
supporting information, p. 3427 - 3430 (2013/07/11)
An unusual base-promoted transformation of readily available 4-(2-chloro-5-nitrophenyl)-1,2,3-thia- and selenadiazoles affords a convenient approach toward benzo[b]thiophenes and benzo[b]selenophenes.
A convenient approach towards 2- and 3-aminobenzo[b]thiophenes
Androsov, Dmitry A.,Solovyev, Andrey Y.,Petrov, Mikhail L.,Butcher, Ray J.,Jasinski, Jerry P.
experimental part, p. 2474 - 2485 (2010/06/14)
Reaction of 1-(2-chloro-5-nitrophenyl)ethanone via Willgerodt-Kindler route with primary or secondary amines and sulfur allows a simple, efficient one-pot synthesis of 3-aminobenzo[b]thiophenes. Base-catalyzed transformation of 4-(2-chloro-5-nitrophenyl)-
Synthesis and reactivity of 4-(2-chloro-5-nitrophenyl)-1,2,3-thiadiazole. A novel one-pot synthesis of N-substituted indole-2-thiols
Androsov, Dmitry A.,Neckers, Douglas C.
, p. 5368 - 5373 (2008/02/08)
(Chemical Equation Presented) 4-(2-Chloro-5-nitrophenyl)-1,2,3-thiadiazole undergoes ring opening to produce a thioketene intermediate that reacts with an O- or N-nucleophile, forming an ester or an amide of the aryl-substituted thioacetic acid. Intermole
