774213-92-2

Upstream product

• 774213-93-3 methyl 1-(2-tert-butoxy-2-oxoethyl)-3-cyclohexyl-1H-pyrrolo[2,3-b]pyridine-6-carboxylate 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 178876-82-9 6-amino-5-bromo-pyridine-2-carboxylic acid methyl ester 
• 26893-72-1 6-acetamido-picolinic acid 
• 36052-26-3 methyl 6-aminopyridine-2-carboxylate 

Downstream Products

• 774213-94-4 methyl 1-(2-tert-butoxy-2-oxoethyl)-3-cyclohexyl-2-phenyl-1H-pyrrolo[2,3-b]pyridine-6-carboxylate 
• 774213-96-6 methyl 3-cyclohexyl-1-[2-(dimethylamino)-2-oxoethyl]-2-phenyl-1H-pyrrolo[2,3-b]pyridine-6-carboxylate 
• 774213-95-5 [3-cyclohexyl-6-(methoxycarbonyl)-2-phenyl-1H-pyrrolo[2,3-b]pyridin-1-yl]acetic acid 

Relevant academic research and scientific papers

Identification of thieno[3,2-b]pyrroles as allosteric inhibitors of hepatitis C virus NS5B polymerase

Thieno[3,2-b]pyrroles are a novel class of allosteric inhibitors of HCV NS5B RNA-dependent RNA polymerase which show potent affinity for the NS5B enzyme. Introduction of a polar substituent in the position N1 led to a compound that efficiently blocks subg

INDOLE ACETAMIDES AS INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE

The present invention relates to indole and azaindole compounds of formula (I): wherein X1, X2, X3, X4, A1, Ar1, R1, R2 and n are as defined herein, and pharmaceutically acceptable salts thereof, useful in the prevention and treatment of hepatitis C infections.