77423-05-3

Upstream product

• 4743-17-3 5-Chloroisatoic anhydride 
• 620-05-3 iodomethylbenzene 
• 57384-84-6 1-benzyl-6-chloro-1H-benzo[d][1,3]oxazine-2,4-dione 
• 77422-96-9 4-Benzyl-7-chloro-9-oxo-4,9-dihydro-pyrazolo[5,1-b]quinazoline-2-carboxylic acid 
• 4418-61-5 5-aminotetrazole 

Relevant academic research and scientific papers

Pyrazoloquinazolin-9-ones: A New Series of Antiallergic Agents

A new series of antiallergic agents, pyrazoloquinazolin-9-ones, was synthesized and evaluated for inhibitory effects in the rat reaginic passive cutaneous anaphylaxis (PCA) screen.Several analogues were found to be more potent than cromolyn sodium intravenously.Structure-activity relationships are discussed.One of the compounds, 4,9-dihydro-5-methoxy-9-oxopyrazoloquinazoline-2-carboxylic acid (36), was found to be approximately 250 times more potent than cromolyn sodium intravenously.