774245-44-2

Upstream product

• 1121-60-4 pyridine-2-carbaldehyde 
• 35132-20-8 (R,R)-1,2-diphenylethylenediamine 
• 100-70-9 2-Cyanopyridine 

Downstream Products

• 1372805-01-0 C₄₈H₃₆N₆O₂ 
• 1372805-02-1 C₆₉H₅₁N₉O₃ 
• 1372805-00-9 C₄₆H₃₆N₆O₄S₂ 

Relevant academic research and scientific papers

Iridium-catalyzed highly chemoselective and efficient reduction of nitroalkenes to nitroalkanes in water

An iridium-catalyzed highly chemoselective and efficient transfer hydrogenation reduction of structurally diverse nitroalkenes was realized at very low catalyst loading (S/C = up to 10000 or 20?000), using formic acid or sodium formate as a traceless hydride donor in water. Excellent functionality tolerance is also observed. The turnover number and turnover frequency of the catalyst reach as high as 18?600 and 19?200 h-1, respectively. An inert atmosphere protection is not required. The reactivities of nitroalkenes are dependent on their substitution pattern, and the pH value is a key factor to accomplish the complete conversion and excellent chemoselectivity. Purification of products is achieved by simple extraction without column chromatography. The reduction procedure is facilely amplified to 10 g scale at 10?000 S/C ratio. The potential of this green reduction in enantioselective hydrogenation has been demonstrated.

Diphenyl-imidazoline derivatives, preparation method thereof and anticancer agent

The present invention refers to diphenylimidazolines derivatives, including anticancer number relates to and of manufacturing method, the present invention according to formula 1 compounds represented (in particular, colon cancer) so that the anticancer activity, can be useful as anticancer number. (by machine translation)

Asymmetric benzoylation of meso-hydrobenzoin using a reusable tripodal imidazoline-pyridine-Cu catalyst

Chiral, self-supported, polytopic imidazoline-pyridine ligands were designed and synthesized for use in Cu catalysis. The tripodal imidazoline-pyridine L6-Cu(BF4)2 complex catalyzed the asymmetric p-(tert-butyl)benzoylation of meso-h

A mild and efficient one-pot synthesis of 2-dihydroimidazoles from aldehydes

The reactions of various aldehydes and 1,2-diamines followed by NXS treatment proceed at 0°C-rt to give the corresponding dihydroimidazoles in high yields. The reaction is mild, and many functional groups such as halogens, nitriles, and esters can exist.

Insights into CO/styrene copolymerization by using PdII catalysts containing modular pyridine-imidazoline ligands

Continuing our studies into the effect that N-N′ ligands have on CO/styrene copolymerization, we prepared new C1-symmetrical pyridine-imidazoline ligands with 4′,5′-cis stereochemistry in the imidazoline ring (5) and 4′,5′-trans stereochemistry (6-10) and compared them with our previously reported ligands (1-4). Their coordination to neutral methylpalladium(II) (5a-10a) and cationic complexes (5b-10b), investigated in solution by NMR spectroscopy, indicates that both the electronic and steric properties of the imidazolines determine the stereochemistry of the palladium complexes. The crystal structures of two neutral palladium precursors [Pd(Me)2-nCln-(N-N′)] (n = 1 for 8a; n = 2 for 9a′) show that the Pd-N coordination distances and the geometrical distortions in the imidazoline ring depend on the electronic nature of the substituents in the imidazoline fragment. Density functional calculations performed on selected neutral and cationic palladium complexes compare well with NMR and X-ray data. The calculations also account for the formation of only one or two stereoisomers of the cationic complexes. The performance of the cationic complexes as catalyst precursors in CO/4-tert-butylstyrene copolymerization under mild pressures and temperatures was analyzed in terms of the productivity and degree of stereoregularity of the polyketones obtained. Insertion of CO into the Pd-Me bond, which was monitored by multinuclear NMR spectroscopy, shows that the N ligand influences the stereochemistry of the acyl species formed.