7743-39-7

Basic information

• Product Name: 3,5-bis(acetylamino)benzoic acid
• Synonyms: 3,5-bis(acetylamino)benzoic acid(SALTDATA: FREE)
• CAS NO: 7743-39-7
• Molecular Formula: C₁₁H₁₂N₂O₄
• Molecular Weight: 236.2293
• EINECS: 231-804-1
• Mol File: 7743-39-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 584.4°C at 760 mmHg
• Flash Point: 307.2°C
• Appearance: /
• Vapor Pressure: 1.68E-14mmHg at 25°C
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3,5-bis(acetylamino)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-bis(acetylamino)benzoic acid(7743-39-7)
• EPA Substance Registry System: 3,5-bis(acetylamino)benzoic acid(7743-39-7)

Safety Data

• Hazardous Substances Data: 7743-39-7(Hazardous Substances Data)

Usage

General Description

3,5-bis(acetylamino)benzoic acid, also known as N-acetylgalactosamine, is a chemical compound with the molecular formula C14H15N3O6. It is a derivative of benzoic acid and is commonly used in biochemistry and organic synthesis. 3,5-bis(acetylamino)benzoic acid is often used as a building block for the synthesis of complex organic molecules and is an important intermediate in the production of various pharmaceuticals and organic compounds. It is also a key component of glycosaminoglycans, which are essential for the formation of connective tissues in the human body. Additionally, 3,5-bis(acetylamino)benzoic acid is a valuable tool for studying carbohydrate-protein interactions and is a key component in the development of new and improved drugs for various medical conditions.

InChI:InChI=1/C11H12N2O4/c1-6(14)12-9-3-8(11(16)17)4-10(5-9)13-7(2)15/h3-5H,1-2H3,(H,12,14)(H,13,15)(H,16,17)/p-1

Upstream product

• 535-87-5 3.5-diaminobenzoic acid 
• 108-24-7 acetic anhydride 
• 75-36-5 acetyl chloride 

Downstream Products

• 1713-07-1 2,4,6,triiodo-5-amino-3-acetylaminobenzoic acid 
• 139870-31-8 meso-mono<α-o-(3,5-diacetamidobenzenecarboxamido)phenyl>tris(α,α,α-o-pivalamidophenyl)porphyrin 

Relevant articles and documents

Water soluble lanthanoid benzoate complexes for the kinetic separation of cis/trans-limonene oxide

A new class of water soluble, environmentally friendly, lanthanoid 3,5-diacetamidobenzoate complexes (Ln = La, Gd, Yb) have been synthesized. The La and Gd complexes selectively catalyse hydrolysis of the cis-isomer of limonene oxide allowing for the separation of the trans-isomer (>98:2 dr) in up to 74% yield. Comparative studies with the corresponding chlorides and triflates reveal the lanthanoid benzoate complexes to be more active than the chlorides, but less active, though more selective, than the triflates.

H-bonded oxyhemoglobin models with substituted picket-fence porphyrins: The model compound equivalent of site-directed mutagenesis

Iron(II) complexes of picket-fence-type porphyrins having one of the four pivalamide pickets replaced by a substituent capable of H-bonding have been synthesized as models for oxyhemoglobin. This synthetic approach is analogous to site-directed mutagenesis of the distal residues in oxygen-binding hemoproteins. Rate and equilibrium data for dioxygen binding have been determined to evaluate the effect of the H-bonding substituent and to make comparisons with more passive substituents. The effect of H-bonding on the dioxygen affinity under standard conditions (25 °C, toluene solvent, 1,2-dimethylimidazole as axial ligand) is best illustrated by the ca. 10-fold increase observed when one pivalamide substituent of picket-fence porphyrin is replaced by a phenylurea substituent. Other substituents influence dioxygen adduct stability in a variety of ways to reveal that even with an apparently straightforward systematic approach, there can be considerable difficulty in partitioning the various factors that influence O2 affinity. This applies to both model compounds and mutant proteins.