77480-26-3

Upstream product

• 77415-72-6 2,7-bis(phenylmethyl)-2,7-diazaspiro<4.4>nonane 
• 77415-70-4 2,7-diaza-spiro[4.4]nonane-1,3,6,8-tetraone 
• 140405-39-6 2,7-Dibenzyl-2,7-diazaspiro<4.4>nonane-1,3,6,8-tetraone 
• 77415-69-1 diethyl 3,3-dicyanoglutarate 
• 77415-68-0 2,7-diaza-spiro[4.4]nonane-1,3,8-trione 
• 128243-95-8 2,7-bis(phenylmethyl)-2,7-diazaspiro<4.4>nonane dihydrochloride 

Downstream Products

• 1147423-20-8 tert-butyl 2,7-diazaspiro[4,4]nonane-2-carboxylate hydrochloride 
• 77415-56-6 2,7-Bis-(toluene-4-sulfonyl)-2,7-diaza-spiro[4.4]nonane 
• 77415-75-9 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-1-[7-((R)-3,3,3-trifluoro-2-methoxy-2-phenyl-propionyl)-2,7-diaza-spiro[4.4]non-2-yl]-propan-1-one 
• 2306252-57-1 2,7-diazaspiro[4.4]-nonane-2-carboxylic acid tert-butyl ester 
• 1415484-12-6 C₃₁H₃₇N₇O₂ 
• 77415-55-5 2,7-diazaspiro[4.4]nonane (dihydrobromide) 
• 77480-30-9 2,7-bis-(toluene-4-sulfonyl)-2,7-diaza-spiro[4.4]nonane 
• 77415-75-9 2,7-Bis(α-methoxy-α-(fluoromethyl)phenylacetyl)-2,7-diazaspiro<4.4>nonane 

Relevant academic research and scientific papers

NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES

The invention provides compounds of general formula (I) wherein A, B, p, w, x, y, and z are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

Quinolone Antibacterial Agents Substituted at the 7-Position with Spiroamines. Synthesis and Structure-Activity Relationships

A series of fluoroquinolone antibacterials having the 7-position (10-position of pyridobenzoxazines) substituted with 2,7-diazaspirononane (4b), 1,7-diazaspirononane (5a), or 2,8-diazaspiroundecane (6b) was prepared, and their biological activities were compared with piperazine and pyrrolidine substituted analogues.Most exhibited potent Gram-positive and Gram-negative activity, especially when side chain 4b was N-alkylated.