77495-34-2

Upstream product

• 77850-42-1 [(E)-5,9-Dimethyl-deca-5,9-dien-(E)-ylidene]-((S)-1-phenyl-ethyl)-amine 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 61195-31-1 (E)-5,9-dimethyl-deca-5,9-dienal 
• 77495-32-0 [(E)-5,9-Dimethyl-deca-5,9-dien-(E)-ylidene]-(1-phenyl-ethyl)-amine 

Relevant academic research and scientific papers

BIOMIMETIC POLYENE CYCLIZATIONS - ASYMMETRIC INDUCTION IN THE CYCLIZATION OF A CHIRAL DIENIC IMINE

The acid-catalyzed cyclization of the chiral aldimine prepared from trans-5,9 dimethyldeca-5,9-dienal and (-)S-α-phenyl-ethylamine affords diastereoisomeric amino-5 dimethyl-2,9 octalines, the asymmetric induction being 65 percent in the trans-trans series and 35 percent in the cis-trans series.

Biomimetic Polyene Cyclizations. Asymmetric Induction during the Acid-Catalyzed Cyclization of Chiral Imines

This paper reports the details of a basic study showing that an imino function is suitable to initiate acid-catalyzed cyclizations of polyenes, affording high yields of cyclized products.The additional advantage of such a function is to introduce very easily a chirality on the polyene skeleton by the way of a chiral group linked to nitrogen.The extent of asymmetric induction by a chiral phenethyl group on nitrogen is from 36percent to 65percent, according to the monocyclic or bicyclic nature of the substrate.