77504-17-7Relevant academic research and scientific papers
Organosilicon Reducing Reagents for Stereoselective Formations of Silyl Enol Ethers from α-Halo Carbonyl Compounds
Pramanik, Suman,Rej, Supriya,Kando, Shun,Tsurugi, Hayato,Mashima, Kazushi
, p. 2409 - 2417 (2018/02/23)
Salt-free stereoselective synthesis of silyl enol ethers was achieved by treating α-halo carbonyl compounds with 2,3,5,6-tetramethyl-1,4-bis(trimethylsilyl)-1,4-dihydropyrazine. In this reaction, easily removable trimethylsilyl halides and 2,3,5,6-tetramethylpyrazine were generated as the reaction byproducts. Due to the inertness of the reaction byproducts, we found a one-pot transformation of the in situ generated silyl enol ethers into various α-functionalized carbonyls by reaction with Togni-II reagent or aldehydes.
Mukaiyama aldol reaction catalyzed by mesoporous aluminosilicate
Ito, Suguru,Yamaguchi, Hitoshi,Kubota, Yoshihiro,Asami, Masatoshi
experimental part, p. 700 - 701 (2011/04/21)
In the presence of a mesoporous aluminosilicate Al-MCM-41, aldol reaction of various silyl enol ethers with both aromatic and aliphatic aldehydes proceeded under mild reaction conditions to afford the corresponding O-silylated aldol adducts in high yields. The solid acid catalyst was easily recovered and reusable three times. Copyright
New role of tin(II) compounds in organic synthesis
Mukaiyama, Teruaki,Kobayashi, Shu
, p. 39 - 52 (2007/10/02)
Three new carbon-carbon bond forming reactions by the use of new catalyst systems involving tin(II) compounds are described in this article.The aldol reaction of silyl enol ethers with acetals or aldehydes and the Michael reaction of silyl enol ethers wit
An Efficient and Extremly Mild Catalyst System, Combined Use of Trityl Chloride and Tin(II) Chloride, in the Aldol and Michael Reactions
Mukaiyama, Teruaki,Kobayashi, Shu,Tamura, Masanori,Sagawa, Yukihiro
, p. 491 - 494 (2007/10/02)
The aldol reaction of silyl enol ethers with acetals or aldehydes, and the Michael reaction of silyl enol ethrs with α,β-unsaturated ketones are efficiently catalyzed by the combined use of trityl chloride and tin(II) chloride under extremly mild conditio
