77507-57-4Relevant academic research and scientific papers
Selectivity control in gold-catalyzed hydroarylation of alkynes with indoles: Application to unsymmetrical bis(indolyl)methanes
McLean, Euan B.,Cutolo, Francesca M.,Cassidy, Orla J.,Burns, David J.,Lee, Ai-Lan
supporting information, p. 6977 - 6981 (2020/09/12)
Gold-catalyzed hydroarylation of unactivated alkynes with indoles have previously been reported to proceed with double indole addition to produce symmetrical bis(indolyl)methanes (BIMs). We demonstrate for the first time that the selectivity of the gold-c
Construction of pyrrole- and indole-fused CF3-piperazine derivatives
Tian, Yu-Ting,Zong, Yu-Wei,Nie, Jing,Zhang, Fa-Guang,Ma, Jun-An
, (2019/09/03)
A series of pyrrole- and indole-fused trifluoromethyl-functionalized piperazine derivatives were constructed in moderate to good yields with excellent chemoselectivities via a Pictet-Spengler reaction under mild and operationally simple conditions. The synthetic utility of this protocol was further extended by the facile preparation of indole-fused CF3-1,4-diazocane and enantioenriched CF3-piperazines via a vinylogous Pictet-Spengler reaction and an asymmetric Pictet-Spengler reaction, respectively.
Gold(I) Complexes in Ionic Liquids: An Efficient Catalytic System for the C-H Functionalization of Arenes and Heteroarenes under Mild Conditions
Baron, Marco,Biffis, Andrea
, p. 3687 - 3693 (2019/06/13)
Use of ionic liquids bearing the proper counteranion as reaction solvents allows to boost the reactivity of gold(I) complexes as catalysts in the hydroarylation of alkynes with arenes and heteroarenes. Several commercial complexes of general structure LAu
